Sort   by:  
 Page size 
ProteomicsIQGAP3 bridges matrix stiffness with glioma stem cell maintenance and radioresistance by stabilizing SOX2
Drivers of therapeutic resistance in cancer include evolution of tumor cell heterogeneity and the tumor microenvironment (TME). Here, we found that increased matrix stiffness promotes radioresistance in glioblastoma (GBM) and maintains the tumor cell hierarchy. Differential gene expression revealed ...
ORGANISM(S): Homo sapiens (Human) 
2026-02-11 | PXD072748 | Pride
Cancer stem cell Glioma stem cell Glioblastoma Radiation Matrix stiffness Iqgap3 Sox2 
ProteomicsIQGAP3 bridges matrix stiffness with glioma stem cell maintenance and radioresistance by stabilizing SOX2
Drivers of therapeutic resistance in cancer include evolution of tumor cell heterogeneity and the tumor microenvironment (TME). Here, we found that increased matrix stiffness promotes radioresistance in glioblastoma (GBM) and maintains the tumor cell hierarchy. Differential gene expression revealed ...
ORGANISM(S): Homo sapiens (Human) 
2026-02-11 | PXD072725 | Pride
Cancer stem cell Glioma stem cell Glioblastoma Radiation Matrix stiffness Iqgap3 Sox2 
GenomicsThe function of IQGAP3 in gastric cancer
The function of IQGAP3 in gastric cancer
PRJNA967224 | ENA
GenomicsOncofetal protein IGF2BP1 regulates IQGAP3 expression to maintain stem cell potential in cancer [RIP-Seq]
Oncofetal protein IGF2BP1 regulates IQGAP3 expression to maintain stem cell potential in cancer [RIP-Seq]
PRJNA803993 | ENA
UnknownE2F1 transactivates IQGAP3 and promotes proliferation of hepatocellular carcinoma cells through IQGAP3-mediated PKC-alpha activation.
Not available
S-EPMC6405983 | biostudies-literature
TranscriptomicsOncofetal protein IGF2BP1 regulates IQGAP3 expression to maintain stem cell potential in cancer [RIP-Seq]
We reported earlier that IQGAP3 is an important stem cell factor in rapidly proliferating isthmus stem cells in the stomach. Furthermore, we observed robust induction of IQGAP3 expression in terminally differentiated chief cells and de-differentiated cells following tissue damage. The elevated expre...
ORGANISM(S): Homo sapiens 
2022-09-16 | GSE196238 | GEO
TranscriptomicsOncofetal protein IGF2BP1 regulates IQGAP3 expression to maintain stem cell potential in cancer [RNA-Seq]
We reported earlier that IQGAP3 is an important stem cell factor in rapidly proliferating isthmus stem cells in the stomach. Furthermore, we observed robust induction of IQGAP3 expression in terminally differentiated chief cells and de-differentiated cells following tissue damage. The elevated expre...
ORGANISM(S): Homo sapiens 
2022-09-16 | GSE196405 | GEO
GenomicsOncofetal protein IGF2BP1 regulates IQGAP3 expression to maintain stem cell potential in cancer [RNA-Seq]
Oncofetal protein IGF2BP1 regulates IQGAP3 expression to maintain stem cell potential in cancer [RNA-Seq]
PRJNA804748 | ENA
UnknownIQGAP3 signalling mediates intratumoral functional heterogeneity to enhance malignant growth.
Not available
S-EPMC11874294 | biostudies-literature
UnknownOverexpression and biological function of IQGAP3 in human pancreatic cancer.
Not available
S-EPMC5209493 | biostudies-literature
Sort   by:  
 Page size