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ProteomicsThe role of IRAKM in IL-1β-treated adipocytes
Toll-like receptors/Interleukin-1 receptor (IL-1R) signaling plays an important role in High-fat diet (HFD)-induced adipose tissue dysfunction contributing to obesity-associated metabolic syndromes. Here, we show an unconventional IL-1R-IRAKM (IL-1R-associated kinase M)-Slc25a1 signaling axis in adi...
ORGANISM(S): Mus musculus (Mouse) 
2022-06-09 | PXD031934 | Pride
Irakm Fatty acid synthesis Pgc1a acetylation Adipocytes Slc25a1 
TranscriptomicsRole of IRAKM in IL-33-induced dendritic cell activation
To gain additional insight into the role of IRAKM in dendritic cell activation in response to IL-33 challenge, we profiled transcriptomes of mouse DC2.4 dendritic cell lines with or without IRAKM following IL-33 treatment in vitro. IRAKM-sufficient and deficient DC2.4 cells were cultured overnight i...
ORGANISM(S): Mus musculus 
2015-03-03 | E-GEOD-66431 | biostudies-arrayexpress
TranscriptomicsRole of IRAKM in IL-33-induced dendritic cell activation
To gain additional insight into the role of IRAKM in dendritic cell activation in response to IL-33 challenge, we profiled transcriptomes of mouse DC2.4 dendritic cell lines with or without IRAKM following IL-33 treatment in vitro.
ORGANISM(S): Mus musculus 
2015-03-03 | GSE66431 | GEO
UnknownLoss of NLRP3 increases bacterial cystitis via IRAKM.
Not available
S-EPMC8899148 | biostudies-literature
UnknownIL-1R-IRAKM-Slc25a1 signaling axis reprograms lipogenesis in adipocytes to promote diet-induced obesity in mice.
Not available
S-EPMC9117277 | biostudies-literature
UnknownIRAKM-Mincle axis links cell death to inflammation: Pathophysiological implications for chronic alcoholic liver disease.
Not available
S-EPMC5115953 | biostudies-literature
GenomicsMus musculus
Role of IRAKM in IL-33-induced dendritic cell activation
PRJNA276900 | ENA
UnknownTLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation.
Not available
S-EPMC6264724 | biostudies-literature
UnknownPooled CRISPR screening identifies m6A as a positive regulator of macrophage activation.
Not available
S-EPMC8081357 | biostudies-literature
UnknownLangerhans Cell Modulation in Atopic Dermatitis Is TLR2/SOCS1-Dependent and JAK Inhibitor-Sensitive.
Not available
S-EPMC12444830 | biostudies-literature
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