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GenomicsExpression data from Hela cells upon knock-down of IRF2BP1 and IRF2BP2
Expression data from Hela cells upon knock-down of IRF2BP1 and IRF2BP2
PRJNA679247 | ENA
TranscriptomicsExpression data from Hela cells upon knock-down of IRF2BP1 and IRF2BP2
IRF2BP1 and IRF2BP2 are transcriptional co-regulators that play a role in EGFR signalling and other signalling events. We used microarray analysis to investigate which genes are under control of IRF2BP1 and IRF2BP2
ORGANISM(S): Homo sapiens 
2021-03-01 | GSE161716 | GEO
TranscriptomicsExpression data from Hela cells that express wt or SUMOylation-deficient IRF2BP1 and which are treated with or without EGF after serum starvation
The transcriptional co-regulator IRF2BP1 gets de-SUMOylated after EGF treatment in Hela cells. SUMOylation of IRF2BP1 occurs at position K579. We used microarray analysis to investigate which genes are under control of IRF2BP1 SUMOylation in dependence of EGF treatment.
ORGANISM(S): Homo sapiens 
2020-09-15 | GSE135221 | GEO
GenomicsExpression data from Hela cells that express wt or SUMOylation-deficient IRF2BP1 and which are treated with or without EGF after serum starvation
Expression data from Hela cells that express wt or SUMOylation-deficient IRF2BP1 and which are treated with or without EGF after serum starvation
PRJNA557842 | ENA
ProteomicsFeedback regulation in EGFR signaling involves IRF2BP proteins and temporal control by (de)SUMOylation
Molecular switches are essential modules in signaling networks by enabling a quick response to environmental changes. Here, we describe a role for small ubiquitin-like-modifier SUMO as a molecular switch in epidermal growth factor receptor (EGFR) signaling. Using quantitative mass spectrometry, we c...
ORGANISM(S): Homo sapiens (Human) 
2021-04-13 | PXD018049 | Pride
Irf2bp1 Dusp1 Transcription Irf2bp2 Egf Feedback inhibitor Egfr Sumo Regulation 
TranscriptomicsTranscription and translation profiling by array of yeast eap1 mutants
One common form of translational control is mediated by proteins that bind to the mRNA 5' cap-binding protein eIF4E. These proteins are collectively called 4E binding proteins (4EBPs). Saccharomyces cerevisiae possesses two 4EBPs that are encoded by non-essential genes called CAF20 and EAP1. To dete...
ORGANISM(S): Saccharomyces cerevisiae 
2008-03-01 | E-MEXP-1309 | biostudies-arrayexpress
UnknownTransient deSUMOylation of IRF2BP proteins controls early transcription in EGFR signaling.
Not available
S-EPMC7926235 | biostudies-literature
ProteomicsAndrogen receptor RIME using LNCaP cells
Rapid immunoprecipitation mass spectrometry of endogenous protein (RIME) was conducted to examine interactome of androgen receptor (AR) in LNCaP cells.
ORGANISM(S): Homo Sapiens (human) 
2021-09-10 | PXD024030 | JPOST Repository
UnknownModulation of interferon activity-associated soluble molecules by appendicitis and appendectomy limits colitis-identification of novel anti-colitic targets.
Not available
S-EPMC4312794 | biostudies-literature
UnknownQuantitative proteome profiling of lymph node-positive vs. -negative colorectal carcinomas pinpoints MX1 as a marker for lymph node metastasis.
Not available
S-EPMC4192020 | biostudies-literature
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