Sort   by:  
 Page size 
TranscriptomicsTranscriptome analysis of MENXM-bM-^@M-^Qassociated rat pituitary adenomas identifies novel molecular mechanisms involved in the pathogenesis of human pituitary gonadotroph adenomas
Gonadotroph adenomas comprise 15M-bM-^@M-^S40 % of all pituitary tumors, are usually non-functioning and are often large and invasive at presentation. Surgery is the first-choice treatment, but complete resection is not always achieved, leading to high recurrence rates. As gonadotroph adenomas poorl...
ORGANISM(S): Rattus norvegicus 
2013-07-10 | E-GEOD-23207 | biostudies-arrayexpress
TranscriptomicsDynamics of gene expression changes in epithelial and mesenchymal HMLER cell lines transitioning from suspension 3D culture to adhesion cultures
In order to metastasize, few cells need to detach from the primary tumor, and transition through the circulation to distant sites to establish new solid tumor metastases. The gene expression changes occurring between these transitions are poorly understood, and controversial findings have been repor...
ORGANISM(S): Homo sapiens 
2015-07-10 | E-GEOD-70279 | biostudies-arrayexpress
TranscriptomicsDynamics of gene expression changes in epithelial and mesenchymal HMLER cell lines transitioning from suspension 3D culture to adhesion cultures
In order to metastasize, few cells need to detach from the primary tumor, and transition through the circulation to distant sites to establish new solid tumor metastases. The gene expression changes occurring between these transitions are poorly understood, and controversial findings have been repor...
ORGANISM(S): Homo sapiens 
2015-07-10 | GSE70279 | GEO
TranscriptomicsMET after transient Twist activation results in de novo gain of malignant traits
During Epithelial-Mesenchymal Transition (EMT), apical-basal polarized epithelial cells are converted to front-to-back polarized mesenchymal cells that only form loose cell-cell adhesions. These phenotypic changes are accompanied by acquisition of increased motility and invasiveness. EMT programs ar...
ORGANISM(S): Homo sapiens 
2015-07-02 | E-GEOD-61206 | biostudies-arrayexpress
UnknownGenetic and Phenotypic Diversity of Morganella morganii Isolated From Cheese.
Not available
S-EPMC8638253 | biostudies-literature
TranscriptomicsSimple Derivation of Transgene-Free iPS Cells by a Dual Recombinase Approach
Induced pluripotent stem cells (iPSCs) can be derived from somatic cells by the introduction of the transcription factors Oct4, Sox2, Klf4 and cMyc using various methods. Here, we describe a new approach for the derivation of murine iPSCs using a polycistronic non-viral inducible vector integrated i...
ORGANISM(S): Mus musculus 
2014-03-29 | E-GEOD-51605 | biostudies-arrayexpress
TranscriptomicsFunctional dissection of the Paired domain of Pax6 – distinct roles of subdomains in neurogenesis and proliferation
The transcription factor Pax6 acts as a key developmental regulator in various organs. In the developing brain Pax6 regulates patterning, neurogenesis and proliferation, but how these diverse effects are mediated at the molecular level is not well understood. As Pax6 regulates forebrain development ...
ORGANISM(S): Mus musculus 
2013-03-19 | E-GEOD-35260 | biostudies-arrayexpress
UnknownCOPD basal cells are primed towards secretory to multiciliated cell imbalance driving increased resilience to environmental stressors.
Not available
S-EPMC11137452 | biostudies-literature
TranscriptomicsThe transcription factor Otx2 regulates choroid plexus development and function
The choroid plexuses (ChPs) are the main regulators of cerebrospinal fluid (CSF) composition and thereby also control the composition of a principal source of signaling molecules that is in direct contact with neural stem cells in the developing brain. The regulators of ChP development mediating the...
ORGANISM(S): Mus musculus 
2013-02-05 | E-GEOD-27630 | biostudies-arrayexpress
TranscriptomicsTRNP1 regulates expansion and folding of the mammalian cerebral cortex by control of radial glial fate
Evolution of the mammalian brain encompassed a remarkable increase in size of cerebral cortex, including tangential and radial expansion, but the mechanisms underlying these key parameters are still largely unknown. Here, we identified the novel DNA associated protein TRNP1 as a regulator of cerebra...
ORGANISM(S): Mus musculus 
2013-04-26 | E-GEOD-40582 | biostudies-arrayexpress
Sort   by:  
 Page size