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ProteomicsInteraction of iron oxide nanoparticles with human plasma
The Interaction of iron oxide nanoparticles with human plasma was studied.
ORGANISM(S): Homo sapiens (Human) 
2019-04-11 | PXD004441 | Pride
Protein corona Inflammation Iron oxide nanoparticles Complement 
ProteomicsQuantitative proteomic analysis of iron oxide nanoparticles toxicity in rats
Iron oxide nanoparticles (IONPs) are the first generation of nanomaterials approved by the Food and Drug Administration for use as imaging agents and for the treatment of iron deficiency in chronic kidney disease. However, several IONPs-based imaging agents have been withdrawn because of toxic effec...
ORGANISM(S): Rattus Norvegicus 
2022-08-11 | PXD035970 |
TranscriptomicsGene expression profiling on FePro labeled bone marrow stromal cells
Superparamagnetic iron oxide nanoparticles (SPION) are increasingly used to label human bone marrow stromal cells (BMSCs, also called mesenchymal stem cells) to monitor their fate by in vivo MRI and histology after Prussian blue (PB) staining. SPION-labeling appears to be safe as assessed by in vitr...
ORGANISM(S): Homo sapiens 
2011-01-24 | E-GEOD-20431 | biostudies-arrayexpress
ProteomicsProteomic profiling reveals the impact of surface functionalization on the protein corona formed on superparamagnetic iron oxide nanoparticles
The protein corona formed on the surface of nanomaterials is critical to understanding their biological behavior, as it is regulated by both the physicochemical properties of the nanomaterials and the physiological environment. The interplay between material synthesis characteristics, protein corona...
ORGANISM(S): Homo Sapiens 
PXD056769 |
ProteomicsIron Oxide Nanoparticles: A Novel Approach to Ameliorating Flood-Induced Oxidative Stress in Maize
This study investigates the proteomic response of maize to flooding stress and evaluates the potential of iron oxide nanoparticles (Fe₂O₃ NPs) in mitigating flood-induced oxidative damage. Proteomic profiles of maize seedlings subjected to flooding, with and without Fe₂O₃ NP treatment, were compared...
ORGANISM(S): Zea Mays 
PXD065195 |
GenomicsDextran-coated Iron Oxide Nanoparticles impairs cardiac function in zebrafish larvae
Dextran-coated Iron Oxide Nanoparticles impairs cardiac function in zebrafish larvae
PRJNA1441529 | ENA
ProteomicsSuper-paramagnetic iron oxide nanoparticles reprogram the tumor microenvironment and reduce lung cancer growth
Tumor associated macrophages (TAMs) are known to play a role in a multitude of processes that facilitate lung cancer growth, including the suppression of tumoricidal immune activation and the absorption of chemotherapeutics. Therefore, deciphering new therapies to reprogram TAMs towards an anti-tumo...
ORGANISM(S): Mus musculus (Mouse) 
2024-04-18 | PXD040145 | Pride
Macrophages Immunotherapy Spion Iron Lung cancer 
TranscriptomicsWhole genome analysis of iron oxide nanoparticles treated mensenchymal stem cells
To determine the cellular effect of iron oxide nanoparticles on MSC, we performed gene expression microarray assay to explore more intensive molecular basis.
ORGANISM(S): Homo sapiens 
2016-04-27 | GSE80695 | GEO
ProteomicsFast and robust proteome screening platform identifies neutrophil extracellular trap formation in the lung in response to cobalt ferrite nanoparticles
The goal of this study was to investigate the effects of magnetic iron cobalt oxide nanoparticles (cobalt doped Fe3O4 nanoparticles with increasing amounts of cobalt) after pulmonary exposure while in parallel presenting a proteomics platform that is easily transferable to large-scale nanotoxicology...
ORGANISM(S): Mus musculus (Mouse) 
2020-03-26 | PXD016148 | Pride
Tmt Iron cobalt oxide nanoparticles Balf Lung Clinical proteomics Nanoparticles Mouse Murine Label-free Metal oxide nanoparticles Bronchoalveolar lavage fluid 
ProteomicsPlasma protein corona on superparamagnetic iron oxide nanoparticles (SPIONs)
We determined the composition of the plasma protein corona on silica-coated versus dextran-coated iron oxide nanoparticles using mass spectrometry-based proteomics approaches. Gene ontology (GO) enrichment analysis and Ingenuity Pathway Analysis (IPA) revealed distinct protein corona compositions fo...
ORGANISM(S): Homo sapiens (Human) 
2015-10-12 | PXD000766 | Pride
Protein corona Superparamagnetic Nanoparticles Mass spectrometry Macrophages 
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