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ProteomicsISDoT: In Situ Decellularization of Tissues for proteomic analysis of native extracellular matrix
The extracellular matrix (ECM) is a master regulator of cellular phenotype and behavior. It plays a critical role in both normal tissue homeostasis and disease pathology. We have developed a fast and efficient approach to enhance the study of ECM composition and structure. Termed In Situ Decellulari...
ORGANISM(S): Homo sapiens (Human) 
2017-06-12 | PXD006579 | Pride
Extracellular matrix Cancer Decellularisation Isdot Biomedical 
ProteomicsTemporal Profiling of PyMT Tumour Matrisome during Progression
In this study, through coupling of our ISDoT tissue decellularisation technology with quantitative mass spectrometry, we explored the changing tumour matrisome during mammary tumourigenesis in the PyMT breast cancer model compared to age-matched healthy control mammary gland
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-03-30 | MSV000089167 | MassIVE
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