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MetabolomicsFunctional analysis of isoprenoid precursors biosynthesis by quantitative metabolomics and isotopologue profiling

INTRODUCTION: Isoprenoids are amongst the most abundant and diverse biological molecules and are involved in a broad range of biological functions. Functional understanding of their biosynthesis is thus key in many fundamental and applicative fields, including systems biology, me...

2021-04-01 | MTBLS923 | MetaboLights
MetabolomicsIntegrated Four Comparative-Omics Reveals the Mechanism of the Terpenoid Biosynthesis in Two Different Overwintering Cryptomeria fortunei Phenotypes
Chinese cedar (Cryptomeria fortunei) is a tree species with important ornamental, medicinal, and economic value. Terpenoids extracted from the essential oil of C. fortunei needles have been considered valuable ingredients in the pharmaceutical and cosmetic industries. However, the poss...
2022-08-12 | MTBLS3183 | MetaboLights
MetabolomicsTranscriptome and Metabolome Analyses Reveal Differences in Terpenoid and Flavonoid Biosynthesis in Cryptomeria fortunei Needles Across Different Seasons

Cryptomeria fortunei (Chinese cedar) has outstanding medicinal value due to its abundant flavonoid and terpenoid contents. The metabolite contents of C. fortunei needles differ across different seasons. However, the biosynthetic mechanism of these differentially synthesized meta...

2022-08-12 | MTBLS4099 | MetaboLights
ProteomicsIsoprenoid alcohols utilization by malaria parasites
Plasmodium falciparum is the etiological agent of human malaria, one of the most widespread diseases in tropical and subtropical world regions. One of the biggest problems in controlling the disease is the emergence of drug resistance, which leads to the need to discover new antimalarial compounds. ...
ORGANISM(S): Homo sapiens (Human) 
2022-11-28 | PXD036092 | Pride
Geranylgeraniol Malaria Dolichols Isoprenoid biosynthesis Phytol Farnesol Fosmidomycin Isoprenoid alcohols Protein dolichylation Plasmodium falciparum Protein prenylation 
TranscriptomicsTranscription profiling of Arabidopsis early post-germinative embryo and endosperm
Arabidopsis seed germination is coordinated with the strong induction of metabolic pathways required for the mobilisation and utilization of seed storage reserves. These are essential to support the seedling before the establishment of photoauxotrophic growth. The activity of genes encoding enzymes ...
ORGANISM(S): Arabidopsis thaliana 
2008-06-14 | E-GEOD-5751 | biostudies-arrayexpress
UnknownTargeting the isoprenoid pathway in choleste biosynthesis: An approach to identify isoprenoid biosynthesis inhibitors.
Not available
S-EPMC11823600 | biostudies-literature
UnknownIsoprenoid biosynthesis in Plasmodium falciparum.
Not available
S-EPMC4248697 | biostudies-literature
UnknownThe isoprenoid alcohol pathway, a synthetic route for isoprenoid biosynthesis.
Not available
S-EPMC6600936 | biostudies-literature
UnknownOn the Origin of Isoprenoid Biosynthesis.
Not available
S-EPMC6107057 | biostudies-literature
UnknownMEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis.
Not available
S-EPMC5567135 | biostudies-literature
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