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MetabolomicsFunctional analysis of isoprenoid precursors biosynthesis by quantitative metabolomics and isotopologue profiling

INTRODUCTION: Isoprenoids are amongst the most abundant and diverse biological molecules and are involved in a broad range of biological functions. Functional understanding of their biosynthesis is thus key in many fundamental and applicative fields, including systems biology, me...

2021-04-01 | MTBLS923 | MetaboLights
UnknownTwo-step pathway for isoprenoid synthesis.
Not available
S-EPMC6329939 | biostudies-literature
ProteomicsImproved synthesis and application of an alkyne-functionalized isoprenoid analogue to study the prenylomes of motor neurons, astrocytes and their stem cell progenitors
Protein prenylation is one example of a broad class of post-translational modifications where proteins are covalently linked to various hydrophobic moieties. To globally identify and monitor levels of all prenylated proteins in a cell simultaneously, our laboratory and others have developed chemical...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2024-05-21 | PXD040354 | Pride
Prenylation Astrocytes Als Chemical enrichment Neurons 
UnknownGrowth-uncoupled isoprenoid synthesis in Rhodobacter sphaeroides.
Not available
S-EPMC7359475 | biostudies-literature
UnknownComplex Ancestries of Isoprenoid Synthesis in Dinoflagellates.
Not available
S-EPMC6664438 | biostudies-literature
UnknownSynthesis of Non-natural, Frame-Shifted Isoprenoid Diphosphate Analogues.
Not available
S-EPMC6020017 | biostudies-literature
TranscriptomicsTranscription profiling of Arabidopsis early post-germinative embryo and endosperm
Arabidopsis seed germination is coordinated with the strong induction of metabolic pathways required for the mobilisation and utilization of seed storage reserves. These are essential to support the seedling before the establishment of photoauxotrophic growth. The activity of genes encoding enzymes ...
ORGANISM(S): Arabidopsis thaliana 
2008-06-14 | E-GEOD-5751 | biostudies-arrayexpress
UnknownIsoprenoid biosynthesis in Plasmodium falciparum.
Not available
S-EPMC4248697 | biostudies-literature
TranscriptomicsSparse feature selection methods identify unexpected global cellular response to strontium-containing materials
Despite the increasing sophistication of biomaterials design and functional characterization studies, little is known regarding cells' global response to biomaterials. Here, we combined nontargeted holistic biological and physical science techniques to evaluate how simple strontium ion incorporation...
ORGANISM(S): Homo sapiens 
2018-11-25 | E-MTAB-7384 | biostudies-arrayexpress
TranscriptomicsProfiling downregulation of the mevalonate pathway in Staphylococcus aureus
Isoprenoids are a class of ubiquitous organic molecules synthesized from the five-carbon starter unit isopentenyl pyrophosphate (IPP). Comprising more than 30,000 known natural products, isoprenoids serve various important biological functions in many organisms. In bacteria, undecaprenyl pyrophospha...
ORGANISM(S): Staphylococcus aureus RN4220 
2010-05-05 | E-GEOD-13424 | biostudies-arrayexpress
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