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Lamina Associated Domains in MEFs depleted of specific lamin isotypes
Purpose: To compare the effects on Lamina Associated Domains (LADs) of shRNA treatment against lamin isotypes. Results: Using an optimized data analysis workflow (LADetector, available at https://github.com/thereddylab/LADetector), We found near identical sequences within the genome-wide maps indica...
ORGANISM(S): Mus musculus 
2020-07-07 | GSE153919 | GEO
Among hematopoietic cells, osteoclasts (Oc) and immature dendritic cells (Dc) are closely related myeloid cells with distinct functions; Oc participate skeleton maintenance while Dc sample the environment for foreign antigens. Such specificities rely on profound modifications of gene and protein exp...
ORGANISM(S): Mus musculus (Mouse) 
2020-09-16 | PXD018832 | Pride
Malondialdehyde-modified epitopes (MDA-epitopes) can elicit specific autoantibody that expressed oxidative stress arising in rheumatoid arthritis (RA). The purpose of this study was to discover and validate MDA-peptide adducts as novel biomarkers using concanavalin A affinity chromatography, 1D SDS-...
ORGANISM(S): Homo sapiens (Human) 
2021-02-25 | PXD004546 | Pride
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