Ito Akihiro A - OmicsDI

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School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Japan (1)
Tokyo University of Pharmacy and Life Sciences (1)

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Pivotal role for S-nitrosylation of DNA methyltransferase in epigenetic regulation

DNMTs catalyze the methylation of cytosine with SAM. DNA methylation affects key cellular processes by regulating gene expression, thus serving a variety of physiological and pathophysiological roles. However, the chemical mechanisms of DNA methylation by which its enzymatic activity is regulated ha...

ORGANISM(S): Homo sapiens (Human)

2023-03-11 | PXD039437 | Pride

The pivotal and universal role of BGLT3 lncRNA in fetal globin gene expression

A highly selective and non-genotoxic G9a inhibitor, RK-701 was discovered, which upregulated the mRNA level of γ-globin but not β-globin both in human erythroid cells and in mice. Using RK-701, we examined the induction of the fetal (γ-) globin protein in human erythroid cells; HUDEP-2 and human CD3...

ORGANISM(S): Homo sapiens (Human)

2023-03-11 | PXD033536 | Pride

Hemoglobin subunit Cultured cell Lc-ms/ms

Post-biopsy proteinuria as a universal prognostic marker across diverse clinical courses in IgA nephropathy.

Not available

S-EPMC12950100 | biostudies-literature

National trends in the outcomes of subarachnoid haemorrhage and the prognostic influence of stroke centre capability in Japan: retrospective cohort study.