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TranscriptomicsIdentification of Myt1 as a subunit of the neural cell type-specific LSD1 complex
Regulation of spatiotemporal gene expression in higher eukaryotic cells is critical for the precise and orderly development of undifferentiated progenitors into committed cell types of the adult. Recently, dynamic epigenomic regulation, including chromatin remodeling and histone modifications by tra...
ORGANISM(S): Mus musculus 
2014-05-20 | E-GEOD-49685 | biostudies-arrayexpress
UnknownSpecific peptide conjugation to a therapeutic antibody leads to enhanced therapeutic potency and thermal stability by reduced Fc dynamics.
Not available
S-EPMC10545826 | biostudies-literature
TranscriptomicsThe induced APL cells generated by the transplantation of PML-RARA-transduced human CD34+ hematopoietic cells into immunodeficient mice
A humanized in vivo APL model has been established utilizing the retroviral transduction of PML-RARA into human CD34+ hematopoietic cells and the transplantation of these cells into immunodeficient mice. The resultant leukemia recapitulated human APL phenotypically, and was clustered in the same cat...
ORGANISM(S): Homo sapiens 
2014-11-04 | E-GEOD-49344 | biostudies-arrayexpress
TranscriptomicsIdentification of mir-342-3p functionally associated with transcriptional activity of MYC in lung cancer [cell culture]
Accumulating evidence indicates that altered miRNA expression is crucially involved in lung cancer development, but only little has been elucidated about how MYC, an archetypical oncogene, is regulated by miRNAs, especially through a mechanism involving the MYC cofactor(s). In this study, we aimed a...
ORGANISM(S): Homo sapiens 
2016-01-06 | E-GEOD-66758 | biostudies-arrayexpress
TranscriptomicsIdentification of mir-342-3p functionally associated with transcriptional activity of MYC in lung cancer [patients]
Accumulating evidence indicates that altered miRNA expression is crucially involved in lung cancer development, but only little has been elucidated about how MYC, an archetypical oncogene, is regulated by miRNAs, especially through a mechanism involving the MYC cofactor(s). In this study, we aimed a...
ORGANISM(S): Homo sapiens 
2016-01-06 | E-GEOD-66759 | biostudies-arrayexpress
ProteomicsProteomics of Human and Mouse serum protein
Proteomics of human and mouse serum protein using nano-LC-MS/MS. In this study, humanized mice serum were included.
ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse) 
2020-09-15 | PXD021477 | JPOST Repository
ProteomicsProteome data on human MDS-L cells
Shotgun mass spectrometric analysis of WT and TOPORS KO MDS-L cells
ORGANISM(S): Homo Sapiens (human) 
2024-03-08 | PXD048275 | JPOST Repository
ProteomicsMS data on ubiquitinated proteins
Mass spectrometric analysis of ubiquitinated proteins in MDS-L cells
ORGANISM(S): Homo Sapiens (human) 
2024-03-08 | PXD044347 | JPOST Repository
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