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TranscriptomicsExpression data from wild-type and HMGN1 knockout mice injected with N-nitrosodiethylamine
HMGN1 contributes to the shortened latency of liver tumorigenesis by changing a chromatin structure and expression of relevant genes To assess the molecular mechanisms underlying accelerated tumor development in Hmgn1-/- mice, we performed the gene expression profiling of liver cells at early stages...
ORGANISM(S): Mus musculus 
2013-08-24 | E-GEOD-44356 | biostudies-arrayexpress
MetabolomicsSequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVID

The post-acute sequelae of COVID-19 (PASC), also known as long COVID, is often associated with debilitating symptoms and adverse multisystem consequences. We obtain plasma samples from 117 individuals during and 6 mth following their acute phase of infection to comprehensively profile and as...

2024-02-23 | MTBLS7337 | MetaboLights
TranscriptomicsControl of RNA stability by NrrF, an iron-regulated small RNA in Neisseria gonorrhoeae.
Regulation of gene expression by small non-coding RNAs (sRNAs) plays a critical role in bacterial response to physiological stresses. NrrF, a trans-acting sRNA in Neisseria meningitidis and Neisseria gonorrhoeae, has been shown in the meningococcus to indirectly control, in response to iron (Fe) av...
ORGANISM(S): Neisseria gonorrhoeae 
2013-09-27 | E-GEOD-48526 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse cardiac samples from OTT1 null/null and OTT1 null/wt embryos
The infant leukemia-associated gene, Ott1(Rbm15), has broad regulatory effects within the murine hematopoiesis. However, germline Ott1 deletion results in fetal demise prior to E10.5, indicating additional developmental requirements for Ott1. The spen gene family, to which Ott1 belongs, has a trans...
ORGANISM(S): Mus musculus 
2008-10-26 | E-GEOD-12628 | biostudies-arrayexpress
MetabolomicsRegulatory T cells promote endurance exercise adaptation by shielding muscle mitochondria from damage

Exercise enhances physical performance and reduces the risk of many disorders such as cardiovascular disease, type 2 diabetes, dementia and cancer. Exercise characteristically incites an inflammatory response, notably in skeletal muscles. While some effector mechanisms have been identified, regul...

2023-10-10 | MTBLS8391 | MetaboLights
UnknownNovel Strategy To Adapt Simian-Human Immunodeficiency Virus E1 Carrying env from an RV144 Volunteer to Rhesus Macaques: Coreceptor Switch and Final Recovery of a Pathogenic Virus with Exclusive R5 Tropism.
Not available
S-EPMC6026739 | biostudies-literature
UnknownInherited CHST11/MIR3922 deletion is associated with a novel recessive syndrome presenting with skeletal malformation and malignant lymphoproliferative disease.
Not available
S-EPMC4585449 | biostudies-literature
UnknownCorticosteroid use and bone mineral accretion in children with asthma: effect modification by vitamin D.
Not available
S-EPMC3387323 | biostudies-literature
UnknownGenetic variation in the immunoglobulin heavy chain locus shapes the human antibody repertoire.
Not available
S-EPMC10362067 | biostudies-literature
UnknownChromothripsis from DNA damage in micronuclei.
Not available
S-EPMC4742237 | biostudies-literature
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