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UnknownCirculating microRNA expression profiles associated with systemic lupus erythematosus.
Not available
S-EPMC6662589 | biostudies-literature
TranscriptomicsTranscription profiling of human cells transfected with a miR-34a LNA inhibitor to investigate its role in oncogene-induced senescence
To understand the role of miR-34a in oncogene-induced senescence, we tested global mRNA expression using microarrays of TIG3 TERT/ deltaB-RAF:ER cells transfected with a miR-34a LNA inhibitor or a scrambled control LNA in the presence or absence of deltaB-RAF activation.
TIG3 TERT/ deltaB-RAF:ER ...
ORGANISM(S): Homo sapiens 
2009-08-01 | E-MEXP-2241 | biostudies-arrayexpress
GenomicsPRDM11: a novel tumor suppressor
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2015-03-02 | E-GEOD-56065 | biostudies-arrayexpress
TranscriptomicsInhibiting Fungal Multidrug Resistance by Disrupting an Activator-Mediator Interaction With the Small Molecule iKIX1
Eukaryotic transcription activators stimulate the expression of specific sets of target genes through recruitment of co-activators such as the RNA polymerase II-interacting Mediator complex. We previously identified an activator-targeted ~85 amino acid three-helix bundle KIX domain in the human MED1...
ORGANISM(S): Saccharomyces cerevisiae 
2015-12-15 | E-GEOD-74361 | biostudies-arrayexpress
GenomicsPlasma DNA - GIS
Data Access Committee EGAC00001001733
EGAC00001001733 | EGA
TranscriptomicsExpression data from EμMyc;Prdm11 WT and EμMyc;Prdm11 KO end-stage splenic tumors
The PR-domain family (PRDMs) encodes transcriptional regulators, several of which are deregulated in cancer. We found that loss of Prdm11 accelerates MYC-driven lymphomagenesis in the Eµ-Myc mouse model. Expression data from EμMyc;Prdm11 WT and EμMyc;Prdm11 KO end-stage splenic tumors to identify ge...
ORGANISM(S): Mus musculus 
2015-03-02 | E-GEOD-56063 | biostudies-arrayexpress
GenomicsPRDM11 ChIP in U2932 cells
The PR-domain family e(PRDMs) encodes transcriptional regulators, several of which are deregulated in cancer. We found that loss of Prdm11 accelerates MYC-driven lymphomagenesis in the Eµ-Myc mouse model. Moreover, we show that patients with PRDM11-deficient diffuse large B cell lymphomas (DLBCLs) h...
ORGANISM(S): Homo sapiens 
2015-03-02 | E-GEOD-56064 | biostudies-arrayexpress
TranscriptomicsEffect of PRDM11 depletion in U2932 cells
The PR-domain family e(PRDMs) encodes transcriptional regulators, several of which are deregulated in cancer. We found that loss of Prdm11 accelerates MYC-driven lymphomagenesis in the Eµ-Myc mouse model. Moreover, we show that patients with PRDM11-deficient diffuse large B cell lymphomas (DLBCLs) h...
ORGANISM(S): Homo sapiens 
2015-03-02 | E-GEOD-56235 | biostudies-arrayexpress
UnknownmiR-34a targets PDGFRA in proneural malignant glioma
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-34242 | biostudies-other
TranscriptomicsmiR-34a targets PDGFRA in proneural malignant glioma
To identify potential targets of miR-34a, we performed transcriptional profiling on proneural TS543 GBM cells, focusing on mRNAs whose levels decreased in response to miR-34a transfection as compared to control oligonucleotide. Proneural TS543 GBM cells were transfected with 100 nM hsa-miR-34a or co...
ORGANISM(S): Homo sapiens 
2012-03-26 | E-GEOD-34242 | biostudies-arrayexpress
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