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TranscriptomicsTranscription profiling of yeast wild type, xrn1, xrn1 upf1, xrn1 nmd2, and xrn1 upf3 strains to investigate mRNA decay
To determine the effects of inactivation of both the nosense-mediated mRNA decay pathway and the general 5' to 3' decay pathway on yeast mRNA decay, we compared the expression profiles of the wild-type, xrn1, xrn1 upf1, xrn1 nmd2, and xrn1 upf3 strains.
ORGANISM(S): Saccharomyces cerevisiae 
2011-11-08 | E-MEXP-27 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast to analyse mRNAs regulated by the nonsense-mediated and 5 to 3 mRNA Decay Pathways
Genome-wide analysis of mRNAs regulated by the nonsense-mediated and 5' to 3' mRNA Decay Pathways in Yeast
ORGANISM(S): Saccharomyces cerevisiae 
2011-11-08 | E-MEXP-26 | biostudies-arrayexpress
ProteomicsRibosome-bound Upf1 forms distinct 80S complexes and conducts mRNA surveillance
Upf1, Upf2, and Upf3 are the central regulators of nonsense-mediated mRNA decay (NMD), the eukaryotic mRNA quality control pathway generally triggered when a premature termination codon is recognized by the ribosome. The NMD-related functions of the Upf proteins likely commence while these factors a...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-10-21 | PXD029577 | Pride
Upf proteins Nmd substrates Ribosome Selective ribosome profiling 
ProteomicsDirect and indirect consequences of PAB1 deletion in the regulation of translation initiation, translation termination, and mRNA decay
Cytoplasmic poly(A)-binding protein (PABPC, yeast Pab1) is involved in various stages of mRNA post-transcriptional control, including translation initiation, translation termination, and mRNA decay regulation. Due to the multi-functional properties of PABPC, attempts to define a specific role for PA...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-06-09 | PXD041495 | Pride
Poly(a)-binding protein Yeast Saccharomyces cerevisiae Pab1 Lc-msms 
TranscriptomicsTranscription profiling of Saccharomyces cerevisiae nmd2::HIS3 GAL-NMD2 strain
The goal of this set of experiments was to identify transcripts that are differentially expressed upon reactivation of NMD in an nmd2::HIS3 strain by galactose-induced expression of the NMD2 gene. Experiment Overall Design: Yeast strains harboring nmd2::HIS3 and the GAL1-NMD2 allele on a plasmid or ...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-16 | E-GEOD-9482 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae edc3 mutant and wild type cultures
The goal of this experiment is to identify transcripts regulated by Edc3p, an activator of mRNA decapping. Experiment Overall Design: Five independent expression profiling experiments were carried out for isogenic wild-type (HFY114) and edc3Δ (CFY25) strains using Affymetrix Yeast Genome S98 Ar...
ORGANISM(S): Saccharomyces cerevisiae 
2007-10-23 | E-GEOD-6647 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae to identify Upf1p-associated transcripts in S. cerevisiae
The goal of this experiment was to identify transcripts associated with the S. cerevisiae Upf1 protein. Experiment Overall Design: The RNA population from four independent pairs of Upf1p-TAP and mock affinity selections were analyzed by using Affymetrix Yeast Genome S98 Arrays.
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-16 | E-GEOD-9486 | biostudies-arrayexpress
GenomicsRibosome-bound Upf1 forms distinct 80S complexes and conducts mRNA surveillance
Ribosome-bound Upf1 forms distinct 80S complexes and conducts mRNA surveillance
PRJNA776169 | ENA
TranscriptomicsSingle-nucleus RNA-seq (10x Genomics Flex) of wild-type C57BL/6J mouse spleen following Plasmodium berghei ANKA infection, generated as a transcriptome-wide reference for the SpatialBench spatial transcriptomics benchmark
This dataset provides single-nucleus RNA-sequencing (snRNA-seq) profiles of wild-type mouse spleen, generated as a matched, transcriptome-wide reference for the SpatialBench resource benchmarking high-resolution spatial transcriptomics platforms (Visium HD, Xenium and MERSCOPE). Spleens were collect...
ORGANISM(S): Mus musculus 
2026-07-07 | E-MTAB-17245 | biostudies-arrayexpress
UnknownTherapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19.
Not available
S-EPMC8362594 | biostudies-literature
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