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ProteomicsMechanistic basis for selective Mediator-dependence of cell type-specifying transcription
The Mediator complex routes signals from DNA-binding transcription factors to RNA polymerase (Pol) II. Despite its pivotal position, mechanistic understanding of Mediator in human cells remains incomplete. Here, we quantified Mediator-controlled Pol II kinetics by coupling rapid subunit degradation ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD017611 | Pride
Chromatin proteomics Human Chromatome Lumos 
UnknownMachine learning enabled multiple illumination quantitative optoacoustic oximetry imaging in humans.
Not available
S-EPMC9203099 | biostudies-literature
UnknownGene expression profiling of porcine mammary epithelial cells after challenge with Escherichia coli and Staphylococcus aureus in vitro.
Not available
S-EPMC4421989 | biostudies-literature
MetabolomicsIntegration of metabolomics, genomics and immune phenotypes reveals the causal roles of metabolites in disease

BACKGROUND: Recent studies highlight the role of metabolites in immune diseases, but it remains unknown how much of this effect is driven by genetic and non-genetic host factors.

RESULT: We systematically investigate circulating metabolites in a cohort of 5...

2021-06-14 | MTBLS2633 | MetaboLights
MetabolomicsLipid Data Analyzer: Analysis of a complex biological system from murine liver samples (Murine liver lipidome experiment)
Lipid Data Analyzer (LDA; http://genome.tugraz.at/lda2) provides automated and reliable annotation of lipid species and their molecular structures in high-throughput data from chromatography-coupled tandem mass spectrometry using embedded rule sets. Using various low- and high-resolution mass spectr...
2017-11-07 | MTBLS396 | MetaboLights
UnknownAge-specific contribution of contacts to transmission of SARS-CoV-2 in Germany.
Not available
S-EPMC9807433 | biostudies-literature
MetabolomicsLipid Data Analyzer: The LDA algorithm against the in silico library LipidBlast (LipidBlast benchmarking experiment)
Lipid Data Analyzer (LDA; http://genome.tugraz.at/lda2) provides automated and reliable annotation of lipid species and their molecular structures in high-throughput data from chromatography-coupled tandem mass spectrometry using embedded rule sets. Using various low- and high-resolution mass spectr...
2017-11-07 | MTBLS397 | MetaboLights
UnknownEffect of risk status for severe COVID-19 on individual contact behaviour during the SARS-CoV-2 pandemic in 2020/2021-an analysis based on the German COVIMOD study.
Not available
S-EPMC10078023 | biostudies-literature
UnknownGuidelines on reporting and assessing dynamic mathematical models of infectious diseases: a scoping review.
Not available
S-EPMC12849597 | biostudies-literature
UnknownThe HABP2 G534E variant is an unlikely cause of familial non-medullary thyroid cancer.
Not available
S-EPMC4803181 | biostudies-literature
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