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TranscriptomicsPolyunsaturated dietary fats decrease mortality and bacterial load during septic S. aureus infection, and improve neutrophil function in mice
Severe infections and sepsis is an increasing clinical problem that cause prolonged morbidity and substantial mortality. At present, antibiotics are essentially the only pharmacological treatment for sepsis. The incidence of antibiotic resistance is increasing and it is therefore critical to find ne...
ORGANISM(S): Mus musculus 
2014-11-24 | E-GEOD-58358 | biostudies-arrayexpress
ProteomicsNormoglycemia and physiological cortisone level maintain glucose homeostasis in a pancreas-liver microphysiological system
Current research on metabolic disorders and diabetes relies on animal models because multi-organ diseases cannot be well studied with the standard in vitro assays. Here, we connect models of key metabolic organs, pancreas and liver, on a microfluidic chip to enable diabetes research in a human-based...
ORGANISM(S): Homo sapiens (Human) 
2024-08-10 | PXD052854 | Pride
Type 2 diabetes mellitus Metabolic disorders Microphysiological system Human pancreatic islets Glucocorticoids Hyperglycemia Transcriptomics Diabetes Proteomics Liver Pancreas 
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