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GenomicsSphingobacterium sp. JB170
Sphingobacterium sp. JB170 complete genome sequence
PRJEB19164 | ENA
ProteomicsProteomics analysis with the Aurora-A PROTAC, JB170
To determine specificity of Aurora-A PROTAC (JB170), MV4-11 cells were labeled with medium containing different stable isotopes (SILAC), treated them with JB170 or Alisertib and subsequently compared their protein content to untreated cells by quantitative mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2020-09-28 | PXD017342 | Pride
Aurora-a Protac Mv4-11 Degronimid Jb170 
ProteomicsProteomics analysis with the Aurora-A PROTAC, JB170
The mitotic kinase Aurora-A is essential for cell cycle progression and considered a priority cancer target. Dozens of ongoing clinical trials are testing the anti-cancer potential of Aurora-A kinase inhibitors. While the catalytic activity of Aurora-A is essential for its function during mitosis, a...
ORGANISM(S): Homo sapiens (Human) 
2020-09-28 | PXD019585 | Pride
Proteomics analysis with the aurora-a protac Jb170 
TranscriptomicsTargeted protein degradation reveals non-catalytic function of Aurora A kinase
RNA Seq in MV4-11 cells after treatment with Alisertib or JB170
ORGANISM(S): Homo sapiens 
2020-07-17 | GSE141911 | GEO
GenomicsTargeted protein degradation reveals non-catalytic function of Aurora A kinase
Targeted protein degradation reveals non-catalytic function of Aurora A kinase
PRJNA595152 | ENA
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