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GenomicsRNA sequencing of JCPyV infection in primary human astrocytes
RNA sequencing of JCPyV infection in primary human astrocytes
PRJNA759925 | ENA
TranscriptomicsRNA sequencing of JCPyV infection in primary human astrocytes
Research in JCPyV infection of primary astrocytes is limited. However, viral infection in a transformed glial cell line (SVGAs), mostly composed of astrocytes, is well studied. RNA sequencing was performed at 24 hours post infection (hpi), 48 hpi, and 96 hpi. Timepoints established to be important i...
ORGANISM(S): Homo sapiens 
2021-09-22 | GSE183322 | GEO
GenomicsGene expression alterations in primary choroid plexus epithelial cells infected with JCPyV
Gene expression alterations in primary choroid plexus epithelial cells infected with JCPyV
PRJNA1101535 | ENA
ProteomicsComprehensive proteomic analysis of JC polyomavirus-infected human astrocytes and their extracellular vesicles
JC polyomavirus (JCPyV) is the causative agent of progressive multifocal leukoencephalopathy (PML), a devastating demyelinating disease of the central nervous system that results in the widespread formation of lesions across the brain parenchyma. The virus is opportunistic and remains in a benign st...
ORGANISM(S): Homo sapiens (Human) JC polyomavirus 
2023-08-28 | PXD044144 | Pride
Pml Astrocytes Hipsc Model Jcpyv 
UnknownIFNα and β Mediated JCPyV Suppression through C/EBPβ-LIP Isoform.
Not available
S-EPMC8537971 | biostudies-literature
UnknownDiscriminating between JCPyV and BKPyV in Urinary Virome Data Sets.
Not available
S-EPMC8230216 | biostudies-literature
UnknownJCPyV miR-J1-5p in Urine of Natalizumab-Treated Multiple Sclerosis Patients.
Not available
S-EPMC8000901 | biostudies-literature
UnknownHigh-throughput drug screen identifies calcium and calmodulin inhibitors that reduce JCPyV infection.
Not available
S-EPMC10922812 | biostudies-literature
TranscriptomicsGene expression alterations in primary choroid plexus epithelial cells infected with JCPyV
The human polyomavirus, JCPyV, establishes a lifelong persistent infection in the peripheral organs of a majority of the human population worldwide. Patients who are immunocompromised due to underlying infections, cancer, or to immunomodulatory treatments for autoimmune disease are at risk for devel...
ORGANISM(S): Homo sapiens 
2024-05-15 | GSE264236 | GEO
UnknownThe MAPK/ERK Pathway and the Role of DUSP1 in JCPyV Infection of Primary Astrocytes.
Not available
S-EPMC8473072 | biostudies-literature
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