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GenomicsH3K14ac is linked to methylation of H3K9 by the Tudor domains of SETDB1
Mononucleosomes were isolated from murine ES cells and precipitated with the recombinant SETDB1 Triple Tudor Domain (3TD), recombinant SETDB1 Triple Tudor domain Y268A mutant, anti-H3K9me2 (Abcam, ab1220), or anti-H3K9me1 (Abcam, ab8896, Lot GR185298-1) antibodies.
ORGANISM(S): Mus musculus 
2018-07-30 | E-MTAB-4982 | biostudies-arrayexpress
GenomicsSETDB1 activity is globally directed by H3K14 acetylation via its Triple Tudor Domain
SETDB1 activity is globally directed by H3K14 acetylation via its Triple Tudor Domain
PRJNA1088534 | ENA
UnknownTargeting oncogenic TERT promoter variants by allele-specific epigenome editing.
Not available
S-EPMC10666398 | biostudies-literature
UnknownDevelopment of super-specific epigenome editing by targeted allele-specific DNA methylation.
Not available
S-EPMC10589950 | biostudies-literature
UnknownSETDB1 activity is globally directed by H3K14 acetylation via its Triple Tudor Domain.
Not available
S-EPMC11662677 | biostudies-literature
GenomicsGenome-wide hydroxymethylcytosine pattern changes in response to oxidative stress
The TET-family enzymes (TETs) convert methylcytosine to hydroxymethylcytosine, a lately discovered epigenetic modification that can modulate transcription. While recent reports suggest that TETs may play a role in response to oxidative stress, this role remains uncertain. Here we show that Tet1 is s...
ORGANISM(S): Homo sapiens 
2016-01-14 | E-GEOD-59718 | biostudies-arrayexpress
TranscriptomicsRegulation of DNA methylation by CK2-mediated phosphorylation of DNMT3A (Beadchip)
DNA methylation is a central epigenetic modification that has essential roles in cellular processes including chromatin structure, gene regulation, development and disease. The de novo DNA methyltransferases are responsible for the generation of genomic methylation patterns, but the underlying mecha...
ORGANISM(S): Homo sapiens 
2014-07-17 | E-GEOD-26164 | biostudies-arrayexpress
ProteomicsProSeAM SILAC MS screening for METTL9 substrates
Click chemistry based substrates screening for METTL9 in Mettl9 KO MEF cells.
ORGANISM(S): Mus Musculus (mouse) 
2020-11-19 | PXD016823 | JPOST Repository
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