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ProteomicsTirzepatide reduces alcohol drinking, modulates reward processing, and alters lateral septum proteome in preclinical models of AUD
This study explored the therapeutic potential of tirzepatide, a dual glucagon-like peptide-1 receptor (GLP-1R)/glucose-dependent insulinotropic polypeptide receptor (GIPR) agonist, in preclinical models of AUD, while elucidating the neurobiological mechanisms mediating its effects. Our methodologica...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-01-23 | PXD063324 | Pride
Alcohol. ethanol Tmt Global quantitative proteomics Tirzepatide Preclinical models 
ProteomicsProteomic And Phosphoproteomic Study Of Placenta And Fetal Liver In Mice With Diet-Induced Obesity
Maternal obesity in mice negatively affects placental functionand maternal and fetal liver function. We performed a global proteomic analysis using a liquid-chromatography/mass-spectrometry system to investigate total and phosphorylated proteins in the placenta and fetal liver in a mouse model that ...
ORGANISM(S): Mus musculus (Mouse) 
2019-01-24 | PXD011722 | Pride
Phosphoproteomics Placenta Lc-ms Liver Tandem mass tag Mouse Obesity 
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