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MetabolomicsCell Membrane Remodeling Mediates Polymyxin B Resistance in Klebsiella pneumoniae: An Integrated Proteomics and Metabolomics Study
Polymyxin B (PB) is introduced into the clinic as the last-line therapy against carbapenem-resistant Klebsiella pneumoniae (CRKP). Unfortunately, increased resistance to PB in Klebsiella pneumoniae (K. pneumoniae) has threatened global health. Resistance of K. pneumoniae ...
2022-03-04 | MTBLS4132 | MetaboLights
ProteomicsRHOF Activation of AKT/β-Catenin Signaling Pathway Drives Acute Myeloid Leukemia Progression and Chemotherapy Resistance
To further investigate which molecules interact with RHOF in AML，we performed a comparative proteomic analysis of 293T cells overexpressing RHOF and control cells using liquid chromatography‒mass spectrometry.
ORGANISM(S): Homo Sapiens 
2024-05-09 | PXD052126 |
ProteomicsPPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1
Our study have shown that PPDPF promoted NF-κB activation through TRIM21-mediated K63-linked ubiquitination of RIPK1 in hepatocytes. Upon TNF-α stimulation, PPDPF enhances TRIM21/RIPK1 interaction and increases TRIM21-mediated K63-linked ubiquitination of RIPK1, which promotes NF-κB activation.To ma...
ORGANISM(S): Homo Sapiens 
2023-02-21 | PXD040301 |
ProteomicsGel-based LC-MSMS, the interactome of XAF1 in 293T cells
We utilized mass spectrometry to analyze the interacting proteins of XAF1 in 293T cells.
ORGANISM(S): Homo Sapiens 
2023-03-22 | PXD041021 |
ProteomicsGPX4 immunoprecipitation in Huh7 cells
Huh7 cells with expression of Flag-GPX4 were treated with IGF1. An immunoprecipitation assay was performed, and immunoprecipitates were subjected to masspec analysis.
ORGANISM(S): Human 
2023-02-22 | MSV000091343 | MassIVE
UnknownComparison of the Oral Calcimimetics Evocalcet and Cinacalcet in East Asian Patients on Hemodialysis with Secondary Hyperparathyroidism.
Not available
S-EPMC10658267 | biostudies-literature
ProteomicsProteomics Analysis of Human Obesity and Metabolic Syndrome Serum
Metabolic syndrome (MS) is a cluster of risk factors that can lead to a disorder of energy utilization and storage and raises risk for heart disease and other health problems. Obesity is a prevalent metabolic disorder in the developed countries and in large parts of developing world that is one of m...
ORGANISM(S): Homo Sapiens 
2022-07-21 | PXD035512 |
ProteomicsProteomics and Human Microchips Identify Thrombospondin-1 as a Potential Biomarker for Calciphylaxis Stem Cell Therapy
Calciphylaxis, also known as calcific uremic arteriolopathy (CUA), is a rare disease with high mortality rate. We effectively rescued CUA patients with novel human amnion-derived mesenchymal stem cell (hAMSC) therapy. Due to the heterogeneity of cutaneous lesion, it is imperative to identify non-inv...
ORGANISM(S): Homo Sapiens 
2026-05-14 | PXD078388 |
UnknownRobust estimation of bacterial cell count from optical density.
Not available
S-EPMC7499192 | biostudies-literature
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