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UnknownHippocampal PPARδ Overexpression or Activation Represses Stress-Induced Depressive Behaviors and Enhances Neurogenesis.
Not available
S-EPMC4772271 | biostudies-literature
TranscriptomicsTranscription profiling of mouse tet inducible NIH 3T3 cells expressing ATPase-defective BRG-1 to identify SWI-SNF-Regulated Genes
NIH 3T3 cells (mouse fibroblasts) were engineered such that the dominant negative ATPase-defective BRG-1 is expressed via the tet-off inducible expression system to inactivate the SWI-SNF chromatin remodeling complexes (Mol Cell Biol 20, 2839). These cell lines have been used for several studies to ...
ORGANISM(S): Mus musculus 
2006-01-01 | E-MEXP-434 | biostudies-arrayexpress
TranscriptomicsGenome-wide binding site of Rec10 and Rec15 during meiosis
Higher-order chromosome structure is assumed to control various DNA-templated reactions in eukaryotes. Meiotic chromosomes implement developed structures called M-bM-^@M-^\axesM-bM-^@M-^] and M-bM-^@M-^\loopsM-bM-^@M-^]; both are suggested to tether each other, activating Spo11 to catalyze meiotic D...
ORGANISM(S): Schizosaccharomyces pombe 
2012-07-27 | E-GEOD-31846 | biostudies-arrayexpress
GenomicsFOXK2 ChIP-seq Illumina
Chromatin immunoprecipitation of FOXK2 (tagged with Flag and His tags) in U2OS cells detected by Illumina sequencing
ORGANISM(S): Homo sapiens 
2014-07-23 | E-MTAB-2204 | biostudies-arrayexpress
UnknownBiomimetic GBM-targeted drug delivery system boosting ferroptosis for immunotherapy of orthotopic drug-resistant GBM.
Not available
S-EPMC8962245 | biostudies-literature
GenomicsDouble fragmentation ChIP-seq provides single nucleotide resolution Tcf4 binding characteristics
ChIP-seq has become the method of choice for studying functional DNA-protein interactions on a genome wide scale. The method is based on co-immunoprecipitation of DNA binding proteins with formaldehyde cross-linked DNA, followed by deep sequencing of immunoprecipitated chromatin fragments, allowing ...
ORGANISM(S): Homo sapiens 
2010-11-01 | E-GEOD-18481 | biostudies-arrayexpress
UnknownChemical Structure-Related Drug-Like Criteria of Global Approved Drugs.
Not available
S-EPMC6273477 | biostudies-literature
GenomicsGenome-wide ATAF1 binding sites in Arabidopsis thaliana
Using a transgenic line expressing HA-tagged ATAF1 uncovered >400 ChIP-seq peaks in ATAF1-HA plants compared to Col-0 wild-type plants. Only a small sub-set of the candidate peaks could be verified using ChIP-qpcr or EMSA. Among the verified peaks we uncovered the key ABA biosynthetic gene NCED3 as ...
ORGANISM(S): Arabidopsis thaliana 
2014-01-01 | E-GEOD-43637 | biostudies-arrayexpress
UnknownArsenene-mediated multiple independently targeted reactive oxygen species burst for cancer therapy.
Not available
S-EPMC8346549 | biostudies-literature
TranscriptomicsCondensin plays a role in both interphase nuclei and premature chromosome condensation
Purpose: to identify how condensin I removal affects gene expression globally. Methods: Chicken DT40 CAP-H KO cells were treated with or without dox for 36 h. Total RNA samples were extracted and subjected to sequencing using an Illumina Hiseq2000 platform. Library preparation and Illumina sequencin...
ORGANISM(S): Gallus gallus 
2017-05-03 | E-GEOD-74892 | biostudies-arrayexpress
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