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Transition metal iron is essential for bacterial survival and growth. For pathogenic bacteria, this challenge is even more severe since human and other mammals have evolved a complicated mechanism of nutritional immunity to restrict iron availability. Preliminary research findings that iron deficien...
ORGANISM(S): Salmonella typhimurium (strain 14028s / SGSC 2262) 
2022-04-27 | PXD023378 | Pride
Gamma-Butyrobetaine Hydroxylase 1 (BBOX1) is a 2-OG dependent enzyme evolving in carnitine synthesis and lipid metabolism. In this study, we propose BBOX1 is a potential tumor suppressor in kidney cancer. We found that BBOX1 is generally underexpressed in ccRCC cells and patients. Restore BBOX1 in c...
ORGANISM(S): Homo sapiens (Human) 
2024-12-23 | PXD050455 | Pride
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