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ProteomicsThe proto-oncogene tyrosine kinase c-SRC facilitates glioblastoma progression by remodeling fatty acid synthesis
Increased fatty acid synthesis benefits glioblastoma malignancy. However, the coordinated regulation of cytosolic acetyl-CoA production, the exclusive substrate for fatty acid synthesis, remains unclear. Here, we show that proto-oncogene tyrosine kinase c-SRC is activated in glioblastoma and remodel...
ORGANISM(S): Homo sapiens (Human) 
2024-07-29 | PXD054314 | Pride
Acss2 Fatty acid synthesis Acly 
UnknownFederated generalized linear mixed models for collaborative genome-wide association studies.
Not available
S-EPMC10387571 | biostudies-literature
UnknownEfficient bidirectional piezo-optomechanical transduction between microwave and optical frequency.
Not available
S-EPMC7054291 | biostudies-literature
MetabolomicsSpermine is a natural suppressor of AR signaling in castration-resistant prostate cancer
In castration-resistant prostate cancer (CRPC), clinical response to androgen receptor (AR) antagonists is limited mainly due to AR-variants expression and restored AR signaling. The metabolite spermine is most abundant in prostate and it decreases as prostate cancer progresses, but its functions re...
2023-10-11 | MTBLS8034 | MetaboLights
UnknownTurboID screening of ApxI toxin interactants identifies host proteins involved in Actinobacillus pleuropneumoniae-induced apoptosis of immortalized porcine alveolar macrophages.
Not available
S-EPMC10360236 | biostudies-literature
UnknownMultidimensional free shape-morphing flexible neuromorphic devices with regulation at arbitrary points.
Not available
S-EPMC11742687 | biostudies-literature
UnknownMammalian-brain-inspired neuromorphic motion-cognition nerve achieves cross-modal perceptual enhancement.
Not available
S-EPMC10008641 | biostudies-literature
ProteomicsCKB catalyzes BCAR1 phosphorylation to regulate DNA damage repair
Creatine kinase (CK) is an essential metabolic enzyme mediating creatine/phosphocreatine interconversion and shuttle to replenish ATP for energy needs. Ablation of CK causes deficiency in energy supply that eventually results in reduced muscle burst activity and neurological disorders in mice. Besid...
ORGANISM(S): Homo Sapiens 
2023-04-05 | PXD041365 |
UnknownA bioinspired flexible neuromuscular system based thermal-annealing-free perovskite with passivation.
Not available
S-EPMC9718817 | biostudies-literature
ProteomicsDifferential Membrane Protein Profile in Sperm
We investigated the differential expression of the total membrane proteins of the two sperm types by using high-purity X- and Y-sperm from 20 Holstein bulls and applying the label-free proteomic technique.
ORGANISM(S): Bos Taurus 
2021-05-18 | PXD019435 |
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