Sort   by:  
 Page size 
UnknownIdentification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study.
Not available
S-EPMC3595425 | biostudies-literature
TranscriptomicsHuman gastric cancer_Tumor samples_Paired normal samples_10 replicates
To identify the lncRNA profiles of gastric cancer samples, we performed microarray analysis using tumor samples and paired normal samples. 66 lncRNAs were statistically dysregulated more than 2-fold. The samples were divided into two groups, paired normal samples (negative control group_Rep10) and t...
ORGANISM(S): Homo sapiens 
2016-07-26 | E-GEOD-84787 | biostudies-arrayexpress
UnknownRestored CD8+PD-1+ T Cells Facilitate the Response to Anti-PD-1 for Patients With Pancreatic Ductal Adenocarcinoma.
Not available
S-EPMC9035626 | biostudies-literature
TranscriptomicsAffymetrix Human Exon 1.0 ST array assay of 15 human MLL-associated samples and 9 human normal bone marrow [HuEx-1_0-st]
To identify potential target genes of leukemia-related miRNAs such as miR-196b and miR-150 in human MLL-associated leukemia, we performed Affymetrix Human Exon 1.0 ST array assay of 15 human MLL-associated samples and 9 human normal bone marrow (including 3 each of CD34+, CD33+, and MNC) cell sample...
ORGANISM(S): Homo sapiens 
2012-08-09 | E-GEOD-34184 | biostudies-arrayexpress
TranscriptomicsBoth gain and loss of function of miR-126 promote t(8;21) leukemia progression with different consequences and through different mechanisms
To investigate the pathological effect of miR-126 on the progression of acute myeloid leukemia (AML) induced by AML1-ETO9a (AE9a), we conducted a series of mouse bone marrow transplantation (BMT) assays with the following groups: AE9a (primary donor cells were wild-type mouse bone marrow progenitor ...
ORGANISM(S): Mus musculus 
2015-09-07 | E-GEOD-65939 | biostudies-arrayexpress
MetabolomicsHuman umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged mice

BACKGROUND: Perioperative neurocognitive disorder (PND) is a key complication affecting older individuals after anesthesia and surgery. Failure to translate multiple pharmacological therapies for PND from preclinical studies to clinical settings has necessitated the exploration o...

2023-07-25 | MTBLS7759 | MetaboLights
TranscriptomicsAffymetrix gene arrays of leukemic BM samples from 24 mice including 9 primary
To identify such targets of leukemia-related miRNAs such as miR-196b, we conducted Affymetrix gene arrays of leukemic BM samples from 24 mice including 9 primary (including 3 each of negative control, MLL-AF9, and miR-196b+MLL-AF9) and 15 secondary (including 3 negative control, 6 MLL-AF9, and 6 miR...
ORGANISM(S): Mus musculus 
2012-08-09 | E-GEOD-34185 | biostudies-arrayexpress
ProteomicsThe NFIB/CARM1 Partnership is a Therapeutic Target for Small Cell Lung Cancer
This project identified NFI family members as CARM1 substrates. NFIB was previously reported to play a critical role in the development of small cell lung cancer. We provided evidence that the arginine methylation of NFIB is required for its oncogenic function in small cell lung cancer.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-11-19 | MSV000090746 | MassIVE
TranscriptomicsIdentification of prognostic gene signatures in AML
Increased expression levels of miR-181 family members have been shown to be associated with favorable outcome in patients with cytogenetically normal acute myeloid leukemia. Here we show that increased expression of miR-181a and miR-181b is also significantly (P < .05; Cox regression) associated wit...
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-30285 | biostudies-arrayexpress
ProteomicsNovel Mechanism and Therapy of Anthracycline-Induced Cardiotoxicity (AIC)
Anthracyclines are potent chemotherapeutic agents known for their efficacy in treating various cancers via inhibition of topoisomerase II alpha (TOP2A). However, their clinical use is limited due to cardiotoxicity, primarily attributed to off-target inhibition of topoisomerase II beta (TOP2B) in car...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-05 | PXD077277 | Pride
Top2b Smyd1 
Sort   by:  
 Page size