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TranscriptomicsExpression data from laser captured gastric neck cells and zymogenic cell from wild type and MIST1 knockout mice
MIST1 is a bHLH transcription factor that is necessary for the maturation of gastric zymogenic cells as they differentiate from their precursor mucous neck cells. In this experiment, mucous neck cells and zymogenic cells of normal, adult C57BL/6 and MIST1 knockout mice were laser-capture microdissec...
ORGANISM(S): Mus musculus 
2013-01-12 | E-GEOD-43441 | biostudies-arrayexpress
ProteomicsNovel functions of the ubiquitin-independent proteasome system in regulating Xenopus germline development
In most species, early germline development occurs in the absence of transcription with germline determinants subject to complex translational and post-translational regulations. Here, we report for the first time that early germline development is influenced by dynamic regulation of the proteasome ...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2019-04-10 | PXD013446 | Pride
Germline development Dnd1 Xenopus Oocyte-to-embryo transition Ubiquitin-independent proteasome 
GenomicsIntegrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this work is comprehensive analysis of target genes co-regulated by CREB1 and FoxA1 in prostate cancer cell models, tissues, and circulating tumor cells (CTCs). Expression of CREB1/...
ORGANISM(S): Homo sapiens 
2016-01-13 | E-GEOD-63034 | biostudies-arrayexpress
TranscriptomicsDifferentially expressed genes of CD11b+Gr-1+ myeloid cells
Differentially expressed genes of CD11b+Gr-1+ immature myeloid cells (IMCs) in the bone marrow and colonic tumor setting of histidine decarboxylase (HDC)-KO mice were examined by microarray (Affymetrix Mouse 430.2 array). Myeloid differentiation-related candidate genes were sought to be isolated and...
ORGANISM(S): Mus musculus 
2010-12-15 | E-GEOD-23502 | biostudies-arrayexpress
GenomicsDATA_SET_ICGC_PedBrainTumor_Medulloblastoma_Discovery_Cohort - samples
DATA_SET_ICGC_PedBrainTumor_Medulloblastoma
EGAD00001000122 | EGA
GenomicsRNA-seq_DATA_SET_ICGC_PedBrainTumor_Medulloblastoma_Discovery_Cohort - samples
ICGC PedBrain: RNA sequencing
EGAD00001000328 | EGA
GenomicsWGS_MATE_PAIR_DATA_SET_ICGC_PedBrainTumor_Medulloblastoma_Discovery_Cohort - samples
release_2: ICGC PedBrain: whole genome mate-pair sequencing
EGAD00001000327 | EGA
GenomicsGoT2D: Genetics of Type 2 Diabetes, a study of the the genetic architecture of type 2 diabetes using low pass whole genome sequencing and high density SNP genotyping in 2,657 individuals.
The Genetics of Type 2 Diabetes Consortium (GoT2D) is a collaboration between the University of Michigan, the Broad Institute and the Wellcome Trust Centre for Human Genetics. The overall aim is to extend upon recent efforts, such as genome-wide association studies (GWAS) and large scale meta-analys...
EGAS00001001459 | EGA
TranscriptomicsGBM-Space: Joint Transcriptome and Chromatin Accessibility Profiling of Glioblastoma (10x Genomics - Multiome)
Cancer cells display highly heterogeneous and plastic states in glioblastoma, an incurable brain tumour. However, how these malignant states arise and whether they follow defined cellular trajectories across tumours is poorly understood. Here, we generated a deep single cell and spatial multi-omic a...
ORGANISM(S): Homo sapiens 
2026-09-12 | E-MTAB-17183 | biostudies-arrayexpress
Genomicsena-DATASET-RTL-11-03-2015-12:07:49:303-16 - samples
Whole genome sequencing was performed with DNA extracted from fresh-frozen tumor and normal material. Short insert DNA libraries were prepared with the TruSeq DNA PCRfree sample preparation kit (Illumina) for paired-end sequencing at a minimum read length of 2x100bp. Human DNA libraries were sequenc...
EGAD00001001273 | EGA
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