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MetabolomicsGut microbiota ameliorates hepatic fibrosis through modulating intestinal bile acid metabolism and hepatocyte pyroptosis (Hepatic fibrosis serum+feces)

Parabacteroides distasonis (P. distasonis) plays an important role in human health, including diabetes, colorectal cancer and inflammatory bowel disease. Here, we show that P. distasonis is decreased in patients with hepatic fibrosis, and that administration of P. dista...

2023-03-17 | MTBLS6728 | MetaboLights
MetabolomicsGut microbiota ameliorates hepatic fibrosis through modulating intestinal bile acid metabolism and hepatocyte pyroptosis (Hepatic fibrosis feces)

Hepatic fibrosis decreased feces bile acid level. Hepatic fibrosis increased serum bile acid. This result showed that hepatic fibrosis inhibited the excretion of bile acid in clinical patients. This result provided phenotype for hepatic fibrosis patients. Bile acid was important indexes for liver...

2023-03-17 | MTBLS6742 | MetaboLights
UnknownIdentification of compound CA-5f as a novel late-stage autophagy inhibitor with potent anti-tumor effect against non-small cell lung cancer.
Not available
S-EPMC6351124 | biostudies-literature
Genomicseaa4975f-4514-44a7-baa4-9404c42156a2 - samples
Whole genome sequencing dataset of 54 tumor/normal samples of 25 cHCC-ICC cases.
EGAD00001005181 | EGA
Genomics61f6508f-ab66-4d36-ad86-028a0ff97746 - samples
The whole exome sequencing data of 291 tumor/normal samples from 121 cHCC-ICC cases.
EGAD00001005183 | EGA
Genomics77745784-0040-45d2-af14-10f27f05a48d - samples
The RNA-seq data of 97 tumor samples from 77 cHCC-ICC cases, data of two other HCC tumor samples were also included.
EGAD00001005182 | EGA
GenomicsGenomic and transcriptomic profiling of combined hepatocellular and intrahepatic cholangiocarcinoma reveals distinct molecular subtypes
We performed genomic and transcriptomic sequencing of 133 combined hepatocellular and intrahepatic cholangiocarcinoma (cHCC-ICC) cases, including separate, combined, and mixed subtypes.
EGAS00001003093 | EGA
GenomicsPKU_cHCC-ICC DAC
Data Access Committee EGAC00001001273
EGAC00001001273 | EGA
ProteomicsDiaphorina citri salivary glands shotgun
In order to identify proteins potentially act as salivary effectors, we conducted proteomic analyses in the SG of D. citri using LC−MS/MS. Two hundred pairs of SG from CLas uninfected D. citri clone were dissected out in SDT lysis buffer. LC−MS/MS analysis was conducted on a Q Exactive mass spectrom...
ORGANISM(S): Diaphorina Citri 
PXD019624 |
MetabolomicsGut microbiota ameliorates hepatic fibrosis through modulating intestinal bile acid metabolism and hepatocyte pyroptosis (Hepatic fibrosis serum)

Hepatic fibrosis decreased feces bile acid level. Hepatic fibrosis increased serum bile acid. This result showed that hepatic fibrosis inhibited the excretion of bile acid in clinical patients. This result provided phenotype for hepatic fibrosis patients. Bile acid was important indexes for liver...

2023-03-17 | MTBLS6732 | MetaboLights
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