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TranscriptomicsDifferentiation of human fetal multipotential neural progenitor cells to astrocytes reveals susceptibility factors for JC Virus
Viral infections of the CNS are of increasing concern, especially among immunocompromised populations. Rodent models are often inappropriate for studies of CNS infection, as many viruses, including JC Virus (JCV) and HIV, cannot replicate in rodent cells. Consequently, human fetal brain-derived mult...
ORGANISM(S): Homo sapiens 
2013-04-09 | E-GEOD-43794 | biostudies-arrayexpress
ProteomicsRapid Histone Post-Translational Modification Analysis Using Alternative Proteases and Tandem Mass Tags (RIPUP)
Histone post-translational modifications (PTMs) alter chromatin dynamics and contribute to the regulation of gene expression in health and disease. Mass spectrometry-based analysis is the gold-standard for histone PTM analysis, but it remains constrained by inefficient sample preparation workflows r...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2026-06-20 | PXD073683 | Pride
Post-translational modifications Histones Proteases Lc-ms/ms 
TranscriptomicsClonal Immortalized Human Glial Cell Lines Support Varying Levels of JC Virus Infection due to Differences in Cellular Gene Expression
JC virus (JCV) is a ubiquitous human polyomavirus that causes the demyelinating disease Progressive Multifocal Leukoencephalopathy (PML). JCV replicates in limited cell types in culture, predominantly in human glial cells. Thus, productive JCV infection is an indicator of the host cell transcription...
ORGANISM(S): Homo sapiens 
2013-10-17 | E-GEOD-45639 | biostudies-arrayexpress
ProteomicsPeakDecoder enables machine learning-based metabolite annotation and accurate profiling in multidimensional mass spectrometry measurements
Global proteomics datasets to study ash utilization by R. toruloides. PeakDecoder is a workflow for metabolite identification and accurate profiling in multidimensional LC-IM-MS-DIA measurements. It is available at https://github.com/EMSL-Computing/PeakDecoder
ORGANISM(S): Rhodosporidium Toruloides Np11 (ncbitaxon:1130832) 
2023-02-03 | MSV000091202 | MassIVE
ProteomicsColorectal cancer anti-ORF1p LFQ IP-MS
Here, three colorectal tumors were subjected to anti-ORF1p LFQ, IP-MS: (A) Krukenberg Carcinoma, Ovary; (B) Metastatic Rectal Adenocarcinoma, Liver; (C) Adenocarcinoma, Colon. These were accompanied by matched normal IP controls and/or mouse IgG IP controls. The objective is to map LINE-1 RNP intera...
ORGANISM(S): Homo sapiens (Human) 
2019-08-23 | PXD013743 | Pride
Lc-msms Patient tumor Line-1 L1 Retrotransposon Crc 
UnknownLineage tracing suggests that ovarian endosalpingiosis does not result from escape of oviductal epithelium.
Not available
S-EPMC7457448 | biostudies-literature
ProteomicsProteogenomic Integration Reveals Therapeutic Targets in Breast Cancer Xenografts
Huang K, Li S, Mertins P, Cao S, Gunawardena HP, Ruggles KV, et al., (2017) Nature Communications | 8:14864 | DOI: 10.1038/ncomms14864 | http://www.nature.com/articles/ncomms14864

Recent advances in mass spectrometry (MS) hav...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2019-08-28 | MSV000084249 | MassIVE
UnknownObserving atmospheric formaldehyde (HCHO) from space: validation and intercomparison of six retrievals from four satellites (OMI, GOME2A, GOME2B, OMPS) with SEAC<sup>4</sup>RS aircraft observations over the Southeast US.
Not available
S-EPMC5880299 | biostudies-literature
UnknownIncidence and Outcomes of Patients With Early Cardiac Complications After Intracerebral Hemorrhage: A Report From VISTA.
Not available
S-EPMC11518970 | biostudies-literature
UnknownInitial interactions with the FDA on developing a validation dataset as a medical device development tool.
Not available
S-EPMC10841854 | biostudies-literature
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