Sort   by:  
 Page size 
ProteomicsSensitive and accurate proteome profiling of embryogenesis using Real-Time Search and TMTproC quantification
Multiplexed proteomics has become a powerful tool for investigating biological systems. Using balancer-peptide conjugates (e.g., TMTproC complementary ions) in the MS2 spectra for quantification circumvents the ratio distortion problem inherent in multiplexed proteomics. However, TMTproC quantificat...
ORGANISM(S): Ciona intestinalis x Ciona robusta Drosophila melanogaster (Fruit fly) Xenopus laevis (African clawed frog) 
2025-01-17 | PXD055647 | Pride
Ciona Tmtpro Xenopus Drosophila Multiplexing Ascend 
MetabolomicsDynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression

Metabolic reprogramming is critical for tumor initiation and progression. However, the exact impact of specific metabolic changes on cancer progression is poorly understood. Here, we integrate multimodal analyses of primary and metastatic clonally-related clear cell renal cancer cells (ccRCC) gro...

2022-12-08 | MTBLS5615 | MetaboLights
UnknownA Therapeutically Targetable NOTCH1-SIRT1-KAT7 Axis in T-cell Leukemia.
Not available
S-EPMC9818047 | biostudies-literature
ProteomicsPharmacological inhibition of the glucocorticoid regenerating enzyme 11ßhydroxysteroid dehydrogenase type 1 after myocardial infarction preserves cardiac function in a translational pig model
Background and Purpose: Adrenal glucocorticoids (GC) increase acutely after myocardial infarction (MI) and thereafter tissue levels are maintained selectively within cells expressing the enzyme 11ßHydroxysteroid Dehydrogenase type 1 (11ßHSD1) that regenerates active GC from circulating metabolites. ...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2026-01-15 | PXD055401 | Pride
Heart Pig 
Genomicsena-DATASET-ICR-GM-05-05-2015-22:13:47:053-131 - samples
463 newly diagnosed patients from the UK Myeloma XI clinical trial (NCT01554852) underwent whole exome sequencing plus targeted capture of the IGH/K/L and MYC loci. 200 ng of DNA were processed using NEBNext DNA library prepartion kit and hybridised to the SureSelect Human All Exon V5 Plus. Four s...
EGAD00001001358 | EGA
Genomics463 newly diagnosed patients with Multiple Myeloma underwent whole exome sequencing of tumour and peripheral blood DNA.
463 newly diagnosed patients from the UK Myeloma XI clinical trial (NCT01554852) underwent whole exome sequencing plus targeted capture of the IGH/K/L and MYC loci. 200 ng of DNA were processed using NEBNext DNA library prepartion kit and hybridised to the SureSelect Human All Exon V5 Plus. Four s...
EGAS00001001147 | EGA
UnknownThe impact of low-mode symmetry on inertial fusion energy output in the burning plasma state.
Not available
S-EPMC10998902 | biostudies-literature
UnknownThe evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance.
Not available
S-EPMC9529057 | biostudies-literature
UnknownSARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses.
Not available
S-EPMC8723827 | biostudies-literature
UnknownPsychological distress and trauma in doctors providing frontline care during the COVID-19 pandemic in the United Kingdom and Ireland: a prospective longitudinal survey cohort study.
Not available
S-EPMC8275363 | biostudies-literature
Sort   by:  
 Page size