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ProteomicsTargeted degradation of extracellular mitochondrial aspartyl-tRNA synthetase modulates immune responses in bacterial pneumonia
The severity of bacterial pneumonia can be worsened by impaired innate immunity resulting in ineffective pathogen clearance. Here We describe a mitochondrial protein, aspartyl-tRNA synthetase (DARS2), which is released in circulation during bacterial pneumonia in humans and displays intrinsic innate...
ORGANISM(S): Homo sapiens (Human) 
2024-08-10 | PXD050224 | Pride
Inflammation Pneumonia Dars2 
UnknownMolecular-level insight into the multiple mechanistic pathways in iron-catalysed alkene dimerisation.
Not available
S-EPMC12571196 | biostudies-literature
UnknownExome sequencing reveals riboflavin transporter mutations as a cause of motor neuron disease.
Not available
S-EPMC3437022 | biostudies-literature
UnknownActivity-dependent endoplasmic reticulum Ca2+ uptake depends on Kv2.1-mediated endoplasmic reticulum/plasma membrane junctions to promote synaptic transmission.
Not available
S-EPMC9335237 | biostudies-literature
UnknownDiscovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor.
Not available
S-EPMC9923840 | biostudies-literature
TranscriptomicsWhole blood gene expression profiles distinguish clinical phenotypes of venous thromboembolism [Set1]
Recurrent venous thromboembolism (VTE) occurs infrequently following a provoked event but occurs in up to 30% of individuals following an initial unprovoked event. We studied 134 patients with VTE separated into 3 groups: (1) ‘low-risk’ patients had ≥1 provoked VTE; (2) ‘moderate-risk’ pa...
ORGANISM(S): Homo sapiens 
2015-11-23 | E-GEOD-48000 | biostudies-arrayexpress
UnknownProlonged Benefit from Ipilimumab Correlates with Improved Outcomes from Subsequent Pembrolizumab.
Not available
S-EPMC4940026 | biostudies-literature
UnknownImpaired sensory processing measured by functional MRI in Bipolar disorder manic and depressed mood states.
Not available
S-EPMC5752628 | biostudies-literature
UnknownThe support that partners or caregivers provide sexual minority women who have cancer: A systematic review.
Not available
S-EPMC8171311 | biostudies-literature
UnknownSex differences in in vivo tau neuropathology in a multiethnic sample of late middle-aged adults.
Not available
S-EPMC8178209 | biostudies-literature
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