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TranscriptomicsInduction of IL-17+ T-cells by HIV-Tat protein is mediated via Vascular Endothelial Growth Factor Receptor-2
Anti-retroviral therapy (ART) has transformed human immunodeficiency virus (HIV) infection from a fatal illness to a chronic condition by controlling viral replication and restoring immune function. However, chronic T-cell activation can be observed in 20-35% of individuals on ART, resulting in an i...
ORGANISM(S): Homo sapiens 
2013-08-02 | E-GEOD-44460 | biostudies-arrayexpress
ProteomicsComparison of control and Elmod1 knockout utricle extracts using tandem mass tagging
Elmod1 knockout mice develop a severe inner ear defect beginning at early postnatal ages. Cuticular plates of utricle hair cells were initially formed normally, then degenerated after postnatal day 5 (P5). Similarly, hair bundles initially were formed normally, but the cell’s apical membrane subsequ...
ORGANISM(S): Mus musculus (Mouse) 
2018-10-24 | PXD006164 | Pride
Arf6 Inner ear Ptprq Vestibular Myo6 Hair cells Actin Elmod1 
UnknownNiraparib and abiraterone acetate plus prednisone for HRR-deficient metastatic castration-sensitive prostate cancer: a randomized phase 3 trial.
Not available
S-EPMC12705445 | biostudies-literature
UnknownSJS/TEN 2019: From science to translation.
Not available
S-EPMC7261636 | biostudies-literature
UnknownHLA-B Alleles with Shared Peptide Binding Specificities Define Global Risk of Cotrimoxazole-induced SCAR.
Not available
S-EPMC12148054 | biostudies-literature
UnknownVEGFR1 signaling in retinal angiogenesis and microinflammation.
Not available
S-EPMC8385046 | biostudies-literature
TranscriptomicsDNA:RNA Immunoprecipitation and Tiling Microarray (DRIP-chip)
Experiment to obtain the genome-wide distribution of DNA:RNA hybrid prone loci in Saccharomyces cerevisiae by DNA:RNA immunoprecipitation and tiling microarray (DRIP-chip). Samples: wild type, Rnase H deletion mutant, hpr1 deletion mutant, sen1-1 temperature sensitive mutant.
ORGANISM(S): Saccharomyces cerevisiae 
2014-05-06 | E-MTAB-2388 | biostudies-arrayexpress
UnknownSafety and clinical activity of a combination therapy comprising two antibody-based targeting agents for the treatment of non-Hodgkin lymphoma: results of a phase I/II study evaluating the immunoconjugate inotuzumab ozogamicin with rituximab.
Not available
S-EPMC4878046 | biostudies-literature
GenomicsGenome wide binding of ATF4 and CEBPG bZIP transcription factors in MEFs under amino acid deprived (AAD) conditions
The integrated stress response (ISR) controls cellular adaptations to nutrient deprivation, redox imbalances and ER stress. ISR genes are upregulated in stressed cells, primarily by the bZIP transcription factor ATF4 through its recruitment to cis-regulatory C/EBP:ATF response elements (CAREs) toget...
ORGANISM(S): Mus musculus 
2015-11-19 | E-GEOD-75165 | biostudies-arrayexpress
TranscriptomicsMetabolic Reprogramming During Purine Stress in the Protozoan Pathogen Leishmania donovani
The ability of Leishmania to survive in their insect or mammalian host is dependent upon an ability to sense and adapt to changes in the microenvironment. However, little is known about the molecular mechanisms underlying the parasite response to environmental changes, such as nutrient availability....
ORGANISM(S): Leishmania donovani 
2014-02-01 | E-GEOD-48394 | biostudies-arrayexpress
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