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ProteomicsMolecular signatures of membrane protein complexes underlying muscular dystrophy
Mutations in genes encoding components of the sarcolemmal dystrophin-glycoprotein complex (DGC) are responsible for a large number of muscular dystrophies. As such, molecular dissection of the DGC is expected to both reveal pathological mechanisms, and provides a biological framework for validating ...
ORGANISM(S): Mus musculus (Mouse) 
2016-04-22 | PXD004020 | Pride
Mouse Glycoproteomics Sucrose fractionation Directed ms Skeletal muscle 
ProteomicsMolecular signatures of membrane protein complexes underlying muscular dystrophy
Mutations in genes encoding components of the sarcolemmal dystrophin-glycoprotein complex (DGC) are responsible for a large number of muscular dystrophies. As such, molecular dissection of the DGC is expected to both reveal pathological mechanisms, and provides a biological framework for validating ...
ORGANISM(S): Mus musculus (Mouse) 
2020-03-12 | PXD002846 | Pride
Mouse Directed ms (dms) Skeletal muscle Membrane protein complexes 
UnknownPost-Traumatic Stress Disorder and Risk of Degenerative Synucleinopathies: Systematic Review and Meta-Analysis.
Not available
S-EPMC11388697 | biostudies-literature
TranscriptomicsTranscriptomic analysis of human skin Langerhans cell and dermal dendritic cells stimulated in vitro with TNF-alpha
Langerhans cells (LCs) are antigen presenting cells residing in the epidermis. Due to the difficulties with obtaining sufficient quantities of LCs for functional studies, many controversies exist about their origin and function. To gain insights into the molecular mechanisms underpinning LC biology ...
ORGANISM(S): Homo sapiens 
2013-12-08 | E-GEOD-49475 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat normal (control) and diabetic animals left ventricle heart tissue
Analysis of gene expression changes in the LV of a rodent heart that occur with uncontrolled diabetes; We used microarrays to detail the global changes that occur in gene expression in the LV of the heart as a result of STZ-induced diabetes. Experiment Overall Design: Male wistars were anaesthetised...
ORGANISM(S): Rattus norvegicus 
2008-06-13 | E-GEOD-5606 | biostudies-arrayexpress
UnknownMolecular Signatures of Membrane Protein Complexes Underlying Muscular Dystrophy.
Not available
S-EPMC5083101 | biostudies-literature
TranscriptomicsTranscription profiling of mouse CD34-enriched keratinocyte stem cells
Recent developments in animal models (Morris et al., 2004; Tumbar et al., 2004) as well as the discovery of cell surface markers (Jones and Watt, 1993; Tani et al., 2000; Trempus et al., 2003; Nijhof et al., 2006) have made it possible to isolate living epidermal hair follicle stem cells (HFSCs) fro...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7690 | biostudies-arrayexpress
UnknownTau protein aggregation is associated with cellular senescence in the brain.
Not available
S-EPMC6260915 | biostudies-literature
TranscriptomicsVZV infection of primary keratinocytes
Our aim was to investigate the interaction between epidermal differentiation and VZV infection. By means of a calcium-induced keratinocyte differentiation model and RNA-seq we show VZV infection has a profound effect on differentiating keratinocytes and hijacks the normal process of epidermal gene ...
ORGANISM(S): Homo sapiens 
2014-05-29 | E-MTAB-1717 | biostudies-arrayexpress
GenomicsSemiconductor-based sequencing of genome-wide DNA methylation states
Methylated DNA immunoprecipitation sequencing (MeDIP-Seq) is a widely used approach to study DNA methylation genome-wide. Here, we present a novel MeDIP-Seq protocol compatible with the Ion Torrent semiconductor-based sequencing platform that is scalable and accurately identifies sites of differe...
ORGANISM(S): Homo sapiens 
2015-06-10 | E-GEOD-61968 | biostudies-arrayexpress
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