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UnknownDiet induced the change of mtDNA copy number and metabolism in Angus cattle.
Not available
S-EPMC7372754 | biostudies-literature
GenomicsPolycomb Repressor Complex 2 and REST-associated histone deacetylases are independent pathways toward a mature neuronal phenotype.
These experiments were designed to test the hypothesis that REST and Polycomb Repressor Complex 2 function cooperatively in undifferentiated ESCs. Our results showed that a majority of REST-bound genomic regions were not associated with H3K27me3 enrichment and loss of H3K27me3 enrichment was not a g...
ORGANISM(S): Mus musculus 
2014-09-30 | E-GEOD-48320 | biostudies-arrayexpress
ProteomicsIntegrin adhesion complex (IAC) analysis from human pancreatic ductal cells (HPDE)
Pancreatic ductal adenocarcinoma (PDAC) is characterised by an abundant desmoplastic reaction which includes an excess production of extracellular matrix and interacts with integrin adhesion receptors. Integrin adhesion complexes formed by HPDE cells (H6c7), with and without expression of mutant KRa...
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD027827 | Pride
Pdac Integrin 
UnknownHeterologous microProtein expression identifies LITTLE NINJA, a dominant regulator of jasmonic acid signaling.
Not available
S-EPMC7584889 | biostudies-literature
ProteomicsCell-derived extracellular matrix (CDM) from human pancreatic ductal cells (HPDE)
Pancreatic ductal adenocarcinoma (PDAC) is characterised by an abundant desmoplastic reaction which includes an excess production of extracellular matrix. The extracellular matrix produced by HPDE cells (H6c7), with and without expression of mutant KRas G12V, was analysed by LC-MSMS
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD027803 | Pride
Ecm Pdac 
TranscriptomicsPolycomb Repressor Complex2 and REST-associated histone deacetylases are independent pathways toward a mature neuronal phenotype
These experiments were designed to test the hypothesis that REST and Polycomb Repressor Complex 2 function cooperatively in undifferentiated ESCs. Our results show that H3K27me3-enriched genes show no de-repression in REST-/- ESCs, while REST target genes show significant de-repression. RNA-seq was ...
ORGANISM(S): Mus musculus 
2014-09-30 | E-GEOD-59442 | biostudies-arrayexpress
ProteomicsA microenvironment-inspired synthetic 3D model for pancreatic ductal adenocarcinoma organoids - PDA Matrisome
LFQ analysis of matrisome fractions enriched from 12 murine PDA or PanIN samples (samples 1 - 12) and a normal pancreas pool (samples 13) pooled from 10 pancreata of C57-Bl6 animals. Three independent enrichments have been conducted for each sample with each having had four injections.
ORGANISM(S): Mus musculus (Mouse) 
2021-11-29 | PXD022767 | Pride
Ecm Pdac Cancer Syntheticmatrix 
ProteomicsA microenvironment-inspired synthetic 3D model for pancreatic ductal adenocarcinoma organoids - Pancreas matrisome atlas
LC-MS/MS based analysis of the normal pancreas matrisome from 10 C57-Black6 animals. Matrisome abundance was quantified using a label-free quantification approach.
ORGANISM(S): Mus musculus (Mouse) 
2021-11-29 | PXD022555 | Pride
Ecm Pdac Organoids Syntheticmatrix Pancreas 
ProteomicsA microenvironment-inspired synthetic 3D model for pancreatic ductal adenocarcinoma organoids - IAC Sets
Integrin adhesion complex (IAC) datasets from KPC-1 and iKRAS cells after 3h or 12h of adhesion on a fibronectin pre-coated surface. IACs were isolated using previously established methods and IACs were investigated using LC-MS/MS.
ORGANISM(S): Mus musculus (Mouse) 
2021-11-29 | PXD022487 | Pride
Tumour Organoids Syntheticmatrice Pdac 
UnknownExamination of the Interpersonal Model With Adolescent Military Dependents at High Risk for Adult Obesity.
Not available
S-EPMC7286799 | biostudies-literature
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