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ProteomicsAnalysis of cardiac ischemia-reperfusion injury using DIA proteomics and N-terminomics
Data used in the publication: Analysis of cardiac ischemia-reperfusion injury using DIA proteomics and N-terminomics reveals alterations in mitochondrial function and metabolism
ORGANISM(S): Rattus (ncbitaxon:10114) 
MSV000092906 | MassIVE
ProteomicsProteomic changes in mouse brain expressing WT and mutant (S3) alleles of the prion protein
Label-free quantification of proteomic changes in mouse expressing WT, mutant (S3) prion protein, and PrP-KO mouse. Three biological replicates were included per condition. In-gel digestion of the proteins extracted from brain generated 6 fractions per replicate.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-07-27 | MSV000092545 | MassIVE
ProteomicsN-terminal acetylation for identification of cleavage sites on immunoprecipitated PrP
In-gel N-terminal acetylation of immunoprecipitated prion protein for identification of cleavage sites. Mouse expressing either WT or mutant (S3) form of PrP were used in this study. Three replicates from single brains were included in this experiment.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-07-27 | MSV000092543 | MassIVE
ProteomicsSubtiligase N-terminomics for identification of cleavage sites in mice brain and immunoprecipitated PrP
Subtiligase-based N-terminomics (Abu N-terminal tagging) of whole mouse brain and immunoprecipitated prion protein. Mouse expressing either WT or mutant (S3) form of PrP were used in this study. Five replicates for single brain experiments and one replicate for combined brains approach are included....
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-07-27 | MSV000092542 | MassIVE
ProteomicsIdentification of proteolytic events during C2C12 myoblast differentiation
Identification of product of proteolysis during C2C12 myoblast differentiation using subtiligase N-terminomics. Different cell populations collected during a time-course of differentiation (4 days) were used for N-terminal labeling in a forward degradomics approach (n=2). Day0 population= Myoblasts,...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2024-05-01 | MSV000094657 | MassIVE
ProteomicsLabel-free quantification of proteomic changes during C2C12 myoblast differentiation
Global proteome comparison between five cell populations isolated during a 4-day differentiation process in C2C12 myoblasts. A total of 5 replicates were in-column digested and data was collected in data independent acquisition mode on a Lumos Tribrid instrument for label free-quantification of prot...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2024-05-01 | MSV000094656 | MassIVE
Proteomicsintracellular MMP-2 proteolysis in cardiac tissue
Induced proteolysis of rat heart extracts with recombinant MMP-2 followed by subtiligase-N-terminomics
ORGANISM(S): Rattus (ncbitaxon:10114) 
2023-11-01 | MSV000093229 | MassIVE
ProteomicsMonkeypox and vaccinia virus infection of primary human astrocytes
Primary human astrocytes were infected with either monkeypox virus (MPXV clade IIb lineage), vaccinia virus (VACV: Acambis 2000), or controls (MC=monkeypox control, AC = Vaccinia control) at an MOI of 10 for 6 h. Samples (n=4) were analyzed by LC-MS/MS with label-free quantification where the data w...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-06-21 | MSV000092229 | MassIVE
ProteomicsLoss of ADAM15 exacerbates transition to decompensated hypertrophy through activation of calcineurin pathway
Label-free quantification of cardiac tissue following transverse aortic constriction (TAC) in a WT and ADAM15-/- mouse model.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-03-07 | MSV000089016 | MassIVE
ProteomicsSARS-CoV-2 Mpro subtiligase-mediated N-terminomics in Jurkat
Subtiligase-based N-terminomics study with 0.5 uM SARS-CoV-2 Mpro in Jurkat cell lysates. Independent duplicates were injected with (L20200924-06, L20200924-07) and without FAIMS (L20200927-01-001, L20200927-02-002).
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-12-17 | MSV000088584 | MassIVE
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