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TranscriptomicsTranscription profiling of juvenile and adult calvarial bone
Background: It has widely been observed that young children are capable of reossifying large calvarial defects, while adults lack this endogenous tissue-engineering capacity. The ability of juvenile animals to regenerate calvarial defects has been investigated in multiple animal models, including mi...
ORGANISM(S): Mus musculus 
2005-07-05 | E-SMDB-3396 | biostudies-arrayexpress
TranscriptomicsJuvenile and adult calvarial bone analysis
Differential transcriptional expression profiles of juvenile and adult calvarial bone. Aalami OO, et al. (2005) Plast Reconstr Surg 115(7):1986-94 Keywords: Logical Set Set of arrays organized by shared biological context, such as organism, tumors types, processes, etc.
ORGANISM(S): Mus musculus 
2010-07-01 | E-GEOD-2896 | biostudies-arrayexpress
ProteomicsTotal and synaptosomal proteomic analysis
Autism spectrum disorders (ASD) represent neurodevelopmental disorders characterized by social deficits, repetitive behaviors, and various comorbidities, including epilepsy. ANK2, which encodes a neuronal scaffolding protein, is frequently mutated in ASD, but its in vivo functions and disease-relate...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-03-19 | MSV000091510 | MassIVE
TranscriptomicsTranscription profiling of mouse adult and juvenile dura mater (bone) to explore the reossification of large calvarial defects during development
BACKGROUND: Although reossification of large calvarial defects is possible in children, adults lack this tissue engineering capacity. In this study, the authors compared the differences in gene expression between juvenile and adult dura mater using a mouse cDNA microarray with 42,000 unique elements...
ORGANISM(S): Mus musculus 
2006-11-06 | E-SMDB-3845 | biostudies-arrayexpress
TranscriptomicsCharacterization of Directly Regulated Thyroid Hormone Mediated Gene Expression Following Short-Term Perturbations in Thyroid Hormone Levels in Juvenile Mice
We investigated the effects of thyroid hormone disruptions on gene expression in juvenile mice liver to develop a stronger understanding of the mechanisms by which thyroid disrupting chemicals impair development. Gene expression was examined by hybridization of hepatic RNA to Agilent mouse microarr...
ORGANISM(S): Mus musculus 
2012-03-29 | E-GEOD-21307 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of spermatogenesis in juvenile mouse testis and analysis of four germ cell deficient mouse models, time series
Temporal study of the first wave of spermatogenesis in juvenile mouse testis and analysis of four germ cell deficient mouse models.
A series of purified testis cell-types (McCarrey libraries)constituting a focussed gene set was exploited to examine gene expression in prepubertal mouse testis. T...
ORGANISM(S): Mus musculus 
2006-08-10 | E-MEXP-571 | biostudies-arrayexpress
ProteomicsProteomic analysis of Adnp mutant mice
We report age-differential synaptic plasticity deficits associated with cognitive inflexibility and CaMKIIa hyperactivity in Adnp-mutant mice. These mice show impaired and inflexible contextual learning and memory additional to social and anxiety-related deficits in adults long after a marked decrea...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
MSV000090257 | MassIVE
OtherType 1 Diabetes Prone NOD Mice Have Diminished Cxcr1 mRNA Expression in Polymorphonuclear Neutrophils and CD4+ T Lymphocytes.
Data from ProteomeXchange, PXD ID: PXD003015. File: OB07268.mzml. Published as part of PLoS One. 2015 Jul 31;10(7):e0134365 . From the Abstract: {{i}} ... Here, we report descriptive data about the Cxcr1 gene in NOD mice ... {{/i}}
ORGANISM(S): Mus_musculus_viruses, Mouse 
GPM32310024995 | GPMDB
Resource Reanalysis 
TranscriptomicsRNA-seq analysis of single cells of the oligodendrocyte lineage from nine distinct regions of the anterior-posterior and dorsal-ventral axis of the mouse juvenile central nervous system
5069 transcriptomes of single oligodendrocyte cells from spinal cord, substantia nigra-ventral tegmental area, striatum, amygdala, hypothalamic nuclei, zona incerta, hippocampus, and somatosensory cortex of male and female mice between post-natal day 21 and 90. The study aimed at identifying diverse...
ORGANISM(S): Mus musculus 
2016-06-10 | E-GEOD-75330 | biostudies-arrayexpress
TranscriptomicsEvidence that variation in adult body size among mammalian species is achieved by modulating the pace of a growth-regulating genetic program
Body size varies enormously among mammalian species. In small mammals, body growth is typically suppressed rapidly, within weeks, whereas in large mammals, growth is suppressed slowly, over years, allowing for a greater adult size. We recently reported evidence that body growth suppression in rodent...
ORGANISM(S): Ovis aries 
2014-05-19 | E-GEOD-48916 | biostudies-arrayexpress
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