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ProteomicsSite-specific K63 ubiquitinomics reveals stabilization of ribosomes in response to oxidative stress
Reprograming of protein synthesis is an essential cellular process to tolerate and resist to stressing conditions. A variety of mechanisms are known to regulate translation at initiation but cells can also control proteins synthesis after the initiation checkpoint. We previously showed that K63 ubiq...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2018-12-06 | PXD004650 | Pride
Ubiquitinomics Yeast Oxidative stress K63 ubiquitin Translation regulation 
ProteomicsK63 polyubiquitination is a new modulator of the oxidative stress response, shotgun data
Ubiquitination is a post-translational modification that signals multiple processes, including protein degradation, trafficking and DNA repair. Polyubiquitin accumulates globally during the oxidative stress response, and this has been mainly attributed to increased ubiquitin conjugation and perturba...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2015-01-26 | PXD000960 | Pride
K63 ubiquitination yeast oxidative stress 
ProteomicsK63 polyubiquitin targets in the amygdala across the lifespan
K63 polyubiquitin targets in the amygdala across the lifespan
ORGANISM(S): Rattus norvegicus (Rat) 
2025-06-18 | PXD058253 | Pride
Amygdala K63 Memory Ubiquitin Aging 
ProteomicsK63 polyubiquitin targets in the hippocampus across the lifespan
K63 polyubiquitin targets in the hippocampus across the lifespan
ORGANISM(S): Rattus norvegicus (Rat) 
2025-06-18 | PXD058248 | Pride
Hippocampus K63 Memory Ubiquitin Aging 
ProteomicsK63 polyubiquitin targets in the hippocampus of male and female rats following contextual fear conditioning
This experiment examined K63 polyubiquitin protein targets in the male and female hippocampus after contextual fear conditioning. Samples were the CA1 region of the dorsal hippocampus collected from male and female Sprague-Dawley rats that were 8-9 weeks old. Samples were collected 1 hour after cont...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-12-02 | PXD054726 | Pride
Hippocampus Sex difference K63 Memory Ubiquitin 
ProteomicsK63 polyubiquitin targets in the hippocampus of male and female rats following contextual fear conditioning
This experiment examined K63 polyubiquitin protein targets in the male and female hippocampus after contextual fear conditioning. Samples were the CA1 region of the dorsal hippocampus collected from male and female Sprague-Dawley rats that were 8-9 weeks old. Samples were collected 1 hour after cont...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-12-02 | PXD054877 | Pride
Hippocampus Sex difference K63 Memory Ubiquitin 
ProteomicsK63 polyubiquitination is a new modulator of the oxidative stress response, SRM data
Ubiquitination is a post-translational modification that signals multiple processes, including protein degradation, trafficking and DNA repair. Polyubiquitin accumulates globally during the oxidative stress response, and this has been mainly attributed to increased ubiquitin conjugation and perturba...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2015-01-26 | PXD000979 | Pride
Q-exactive Yeast Silac Lc-ms/ms 
ProteomicsThe UBA-domain of Ubc1/Ube2K Facilitates the Assembly of K48-/K63-Branched Ubiquitin Chains
Assembly of polymeric ubiquitin (Ub) chains is an essential posttranslational protein modification that regulates widespread intracellular processes in eukaryotic cells. Factors and mechanisms that regulate the formation of Ub chains are key to the understanding of many cellular processes. The E2 en...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-09-09 | PXD018651 | Pride
Ubc1/ube2k ubiquitin k48-/k63-branched ubiquitin prm 
ProteomicsMARCH1 ubiquitination of MHC II generates a branched K63/K11 ubiquitin chain.
Major histocompatibility class II (MHC II) is critical for adaptive immunity. MHC II intracellular trafficking and degradation is regulated by ubiquitination, with poly-ubiquitination (Ub) of MHC II directing it away from the plasma membrane. The MHC II poly-Ub chain that dictates the fate and funct...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-01 | PXD063057 | Pride
Ubiquitin Mhcii Ub-code Aqua peptides 
ProteomicsSex differences in the role of K63 polyubiquitination in the amygdala during fear memory formation
This project examined sex differences in the role of K63 polyubiquitination in the amygdala during context fear memory formation in male and female rats.
ORGANISM(S): Rattus norvegicus (Rat) 
2023-05-18 | PXD036369 | Pride
Sex differences Consolidation Amygdala K63 Memory Ubiquitin 
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