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ProteomicsAlphavirus infection triggers selective cytoplasmic translocation of nuclear RBPs with moonlighting antiviral roles
RNA is a central molecule for RNA viruses, acting as mRNA and genome. However, the interactions that viral (v)RNA establishes with the host cell is only starting to be elucidated. Here, we determine with unprecedented depth the composition of the ribonucleoproteins (RNPs) of the prototypical arthrop...
ORGANISM(S): Homo sapiens (Human) 
2024-12-19 | PXD029492 | Pride
Rna-binding proteins Vric 
ProteomicsSINV-nsP3 mScarelt-tagged immunoprecipitation
1x107 cells HEK293 FLP-IN T-REX cells were infected with SINVnsP3-mScarlet (bait) or SINVwt (negative control) at 1 MOI. After 18 hours, cells were scrapped and spin down at 300 g 4°C for 10 mins. After the centrifugation, supernatants were discarded and cell pellet washed once with 1X PBS, followed...
ORGANISM(S): Homo sapiens (Human) 
2024-12-19 | PXD054117 | Pride
Sinv-nsp3 
ProteomicsGlobal analysis of protein-RNA interactions in SARS-CoV-2 infected cells reveals key regulators of infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19. SARS-CoV-2 relies on cellular RNA-binding proteins (RBPs) to replicate and spread, although which RBPs control SARS-CoV-2 infection remains largely unknown. Here, we employ a multi-omic approach to identify systematically ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD023418 | Pride
Wcp Cric Sars-cov-2 Calu-3 Vric 
ProteomicsWolbachia strains differ in arbovirus inhibition mechanisms in Aedes mosquitoes
Some strains of the inherited bacterium Wolbachia have been shown to be effective at reducing the transmission of dengue and other positive-sense RNA viruses by Aedes aegypti in both laboratory and field settings and are being deployed for dengue control. The degree of virus inhibition varies betwee...
ORGANISM(S): Aedes Aegypti (ncbitaxon:7159) Wolbachia (ncbitaxon:953) 
2023-06-07 | MSV000092124 | MassIVE
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
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