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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19. SARS-CoV-2 relies on cellular RNA-binding proteins (RBPs) to replicate and spread, although which RBPs control SARS-CoV-2 infection remains largely unknown. Here, we employ a multi-omic approach to identify systematically ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD023418 | Pride
RNA is a central molecule for RNA viruses, acting as mRNA and genome. However, the interactions that viral (v)RNA establishes with the host cell is only starting to be elucidated. Here, we determine with unprecedented depth the composition of the ribonucleoproteins (RNPs) of the prototypical arthrop...
ORGANISM(S): Homo sapiens (Human) 
2024-12-19 | PXD029492 | Pride
The coronavirus disease 2019 caused by SARS-CoV-2 has led to an unprecedented health crisis. However, to date, the architecture of the viral RNA genomes inside virions have not been observed because the interiors of viral particles are not visible, even using sophisticated Cryo-electron microscopy a...
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 
2021-03-25 | GSE155733 | GEO
Porcine deltacoronavirus (PDCoV) is a newly emerging and special delta coronavirus, which infect mammals such as pigs, cattle and humans, as well as chickens and birds. Exploring RNA structures in the viral genome benefits the understanding of the role of RNA in the lifecycle of viruses. In this stu...
ORGANISM(S): Sus scrofa 
2024-04-10 | GSE254992 | GEO
The architecture of the SARS-CoV-2 RNA genome inside virion
The architecture of the Porcine deltacoronavirus RNA genome inside virions by vRICseq
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