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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19. SARS-CoV-2 relies on cellular RNA-binding proteins (RBPs) to replicate and spread, although which RBPs control SARS-CoV-2 infection remains largely unknown. Here, we employ a multi-omic approach to identify systematically ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD023418 | Pride
The majority of clinical degraders utilize an immunomodulatory imide drug (IMiD)-based derivative, that directs their target to the E3 ligase receptor Cereblon (CRBN), however, identification of new IMiD molecular glue substrates has remained underexplored. To tackle this, we design human CRBN const...
ORGANISM(S): Homo sapiens (Human) 
2024-12-06 | PXD056863 | Pride
PTM proteomics had been increasingly used in studies related to inflammation and immunity, but the integrated analysis of multiple PTM was lacking. Here, we integrated WCP, acetylome, phosphoproteome and ubiquitinome datasets to identify LPS stimulation-dependent PTM events in macrophages with or wi...
ORGANISM(S): Homo Sapiens Mus Musculus 
2019-09-20 | PXD015527 |
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