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TranscriptomicsClear cell sarcoma of the kidney demonstrates an embryonic signature indicative of a primitive nephrogenic origin
Gene expression profiling of CCSK in comparison with non-neoplastic foetal and adult kidney Total RNA extracted from 22 frozen CCSKs and 6 adult non-neoplastic kidneys and comercially obtained RNA from 4 foetal kidneys, were hybridized to Illumina humanHT-12 v4.0 Expression BeadChip at the SCIBLU L...
ORGANISM(S): Homo sapiens 
2014-08-22 | E-GEOD-49972 | biostudies-arrayexpress
ProteomicsPseudouridylation of tRNA-derived fragments steers translational control in stem cells
Pseudouridylation (Ψ) is the most abundant and widespread type of RNA epigenetic modification in living organisms; however, the biological role of Ψ remains poorly understood. Here, we show that a Ψ-driven posttranscriptional program steers translation control to impact stem cell commitment during e...
ORGANISM(S): Homo sapiens (Human) 
2018-04-11 | PXD008676 | Pride
Dimethyl labelling Trna Pseudouridylation 
TranscriptomicsGas7 male transgenic liver expression vs FVB male wildtype control
A major task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. We previously developed a method to infer causal relationships among genes through the integration of DNA variation, gene transcription, and phenotypic information. Here we validated our m...
ORGANISM(S): Mus musculus 
2009-03-07 | E-GEOD-11996 | biostudies-arrayexpress
TranscriptomicsGpx3 male transgenic liver expression vs B6/DBA male wildtype control
A major task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. We previously developed a method to infer causal relationships among genes through the integration of DNA variation, gene transcription, and phenotypic information. Here we validated our m...
ORGANISM(S): Mus musculus 
2009-03-07 | E-GEOD-11997 | biostudies-arrayexpress
TranscriptomicsGyk female heterozygous liver expression vs C57Bl/6J female wildtype control
A major task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. We previously developed a method to infer causal relationships among genes through the integration of DNA variation, gene transcription, and phenotypic information. Here we validated our m...
ORGANISM(S): Mus musculus 
2009-03-07 | E-GEOD-11998 | biostudies-arrayexpress
TranscriptomicsLactb male transgenic liver expression vs FVB male wildtype control
A major task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. We previously developed a method to infer causal relationships among genes through the integration of DNA variation, gene transcription, and phenotypic information. Here we validated our m...
ORGANISM(S): Mus musculus 
2009-03-07 | E-GEOD-11999 | biostudies-arrayexpress
TranscriptomicsObesity study in transgenic and knockout animals
A major task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. We previously developed a method to infer causal relationships among genes through the integration of DNA variation, gene transcription, and phenotypic information. Here we validated our m...
ORGANISM(S): Mus musculus 
2009-03-07 | E-GEOD-12000 | biostudies-arrayexpress
UnknownGenome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.
Not available
S-EPMC4740377 | biostudies-literature
UnknownDevelopment and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study.
Not available
S-EPMC4380415 | biostudies-literature
UnknownNew genetic loci link adipose and insulin biology to body fat distribution.
Not available
S-EPMC4338562 | biostudies-literature
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