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TranscriptomicsHomogeneous monocytes and macrophages from hES cells following coculture-free differentiation in M-CSF and IL-3.
In the present study we aimed at producing homogeneous populations of monocytes and macrophages from human embryonic stem (hES) cells. Human embryonic stem cell lines KCL001, KCL002, and HUES-2 were differentiated into monocytes by coculture-free differentiation with two growth factors using a three...
ORGANISM(S): Homo sapiens 
2010-05-08 | E-GEOD-15791 | biostudies-arrayexpress
ModelsSilber2007_IntravenousGlucose_IntegratedGlucoseInsulinModel
This a model from the article: An integrated model for glucose and insulin regulation in healthy volunteers and type 2 diabetic patients following intravenous glucose provocations. Silber HE, Jauslin PM, Frey N, Gieschke R, Simonsson US, Karlsson MO. J Clin Phar...
2005-01-01 | MODEL1112110004 | BioModels
TranscriptomicsPost-replicative formation of cohesion is required for repair and induced by a single DNA break
Sister chromatid cohesion, established during replication by the protein complex Cohesin, is essential for both chromosome segregation and double-strand break (DSB) repair. Normally cohesion formation is strictly limited to the S-phase of the cell cycle, but DSBs can trigger cohesion also after DNA ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-10 | E-GEOD-8270 | biostudies-arrayexpress
UnknownA Nonlinear Mixed Effects Pharmacokinetic Model for Dapagliflozin and Dapagliflozin 3-O-glucuronide in Renal or Hepatic Impairment.
Not available
S-EPMC3674329 | biostudies-literature
UnknownPhysiologically-based pharmacokinetic models versus allometric scaling for prediction of tyrosine-kinase inhibitor exposure from adults to children.
Not available
S-EPMC11390758 | biostudies-literature
UnknownIlixadencel, a Cell-based Immune Primer, plus Sunitinib Versus Sunitinib Alone in Metastatic Renal Cell Carcinoma: A Randomized Phase 2 Study.
Not available
S-EPMC9142735 | biostudies-literature
UnknownMechanism-Based Modeling of Gastric Emptying Rate and Gallbladder Emptying in Response to Caloric Intake.
Not available
S-EPMC5192972 | biostudies-literature
ProteomicsDIA proteomics of OGG1 inhibition in murine model of fibrosis
Interstitial lung diseases such as idiopathic pulmonary fibrosis (IPF) are caused by persistent micro-injuries to alveolar epithelial tissues accompanied by aberrant repair processes. Despite substantial advancement in our understanding of IPF progression, numerous questions remain concerning diseas...
ORGANISM(S): Mus musculus (Mouse) 
2023-02-06 | PXD029625 | Pride
Lung tissue Mus musculus Mass spectrometry Dia-ms Bronchoalveolar lavage fluid Orbitrap 
ProteomicsTCUP: Typing and characterization of bacteria using bottom-up tandem mass spectrometry proteomics
Methods for rapid and reliable microbial identification are essential in modern healthcare. The ability to detect and correctly identify pathogenic species and their resistance phenotype is necessary for accurate diagnosis and efficient treatment of infectious diseases. Bottom-up tandem mass spectro...
ORGANISM(S): Escherichia coli 
2017-04-20 | PXD004321 | Pride
Tandem mass spectrometry Bottom-up Proteotyping 
UnknownComparing randomized trial designs to estimate treatment effect in rare diseases with longitudinal models: a simulation study showcased by Autosomal Recessive Cerebellar Ataxias using the SARA score.
Not available
S-EPMC12309037 | biostudies-literature
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