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ProteomicsProteomic characterization of sorted peroxisomes
Proteomic analysis of sorted peroxysomes (old, young, and middle-aged).
ORGANISM(S): Homo sapiens (Human) 
2025-03-04 | PXD028679 | Pride
Proteomics Peroxisome 
TranscriptomicsExpression data from Paneth cells isolated from mice on calorie restricted or ad libitum diet
Paneth cells recide in the intestinal crypt bottom and are part of the innate immunity and of the intestinal stem cell niche. We used microarrays to detail the global changes in gene expression following reduced calorie intake. Mice were kept on ad libitum or calorie restricted (60% of calories of a...
ORGANISM(S): Mus musculus 
2012-04-11 | E-GEOD-37209 | biostudies-arrayexpress
MetabolomicsOld mitochondria regulate niche renewal via stem cell metabolism
Cellular metabolism is emerging as a potent regulator of cell fate, raising the possibility that the recently discovered metabolic heterogeneity between newly synthesized and chronologically old organelles may impact stem cell fate in mammalian tissues. The small intestine is maintained by actively ...
2025-04-24 | MTBLS12349 | MetaboLights
TranscriptomicsWhole-genome oxidative bisulfite sequencing and data processing of mouse intestinal stem cells with old and young mitochondria
The intent of the study was to profile the methylome and hydroxymethylome in intestinal stem cells with young mitochondria or old old mitochdondria, to ascertain the potential role of mitochondrial age specific influence on epigenetic regulation of ISCs.
ORGANISM(S): Mus musculus 
2025-05-07 | E-MTAB-15119 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Dm-aKG treated intestinal stem cells (ISCs) and controls
The object of this study was to investigate how aKG impacts mouse intestinal stem cell (ISCs) function and fate decisions in vivo. Mice were treated for 7 days with twice daily aKG IP injections after which ISCs were FACS sorted and transcriptomically anayzled. This revealed a striking set of secret...
ORGANISM(S): Mus musculus 
2025-05-02 | E-MTAB-15105 | biostudies-arrayexpress
UnknownAn integrated spatially defined roadmap of normal and cancer-associated colon fibroblasts
Not available
S-SCDT-10_1038-S44320-026-00247-0 | biostudies-other
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