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Proteomics,MultiomicsComplementary critical functions of Zfy1 and Zfy2 in mouse spermatogenesis and reproduction
The mammalian Y chromosome plays a critical role in spermatogenesis. However, the exact functions of each gene in the Y chromosome have not been completely elucidated, partly owing to difficulties in gene targeting analysis of the Y chromosome. Zfy was first proposed to be a sex determination factor...
ORGANISM(S): Mus <mouse, Genus> (ncbitaxon:10088) 
2016-11-24 | MSV000080355 | MassIVE
ProteomicsSearch for host factors located in the vicinity of the cytoplasmic tails of the mumps virus glycoproteins
Mumps virus (MuV) is the etiological agent of mumps, a disease characterized by painful swelling of the parotid glands and often accompanied by severe complications. To understand the molecular mechanism of MuV infection, a functional analysis of the involved host factors is required. However, littl...
ORGANISM(S): Homo sapiens (Human) 
2022-10-29 | PXD035151 | Pride
Proximity labeling Split-turboid Glycoprotein Mumps virus 
ProteomicsMouse osteoclast-small extracellular vesicles LC-MSMS
Small extracellular vesicles secreted from maturing osteoclasts were collected and analyzed for identifying their protein components
ORGANISM(S): Mus musculus (Mouse) 
2018-09-06 | PXD010500 | Pride
Lc-msms Mouse Osteoclast Small extracellular vesicles 
TranscriptomicsTranscriptome in alveolar epithelial type II-like cells differentiated from human lung progenitor cells
Resident stem/progenitor cells in lungs are important for tissue homeostasis and repair. We isolated human lung progenitor cells and named alveolar epithelial progenitor cells (AEPCs)(Fujino N, et al. 2011. Lab Invest. 91:363). AEPCs have phenotypes of both alveolar epithelial type II (ATII) cells a...
ORGANISM(S): Homo sapiens 
2012-10-11 | E-GEOD-33825 | biostudies-arrayexpress
UnknownStructure and engineering of the type III-E CRISPR-Cas7-11 effector complex
Not available
EMPIAR-11825 | biostudies-other
UnknownStructural mechanism of RNA-guided RNA editing by the Cas13b-ADAR2 REPAIR complex
Not available
EMPIAR-11850 | biostudies-other
TranscriptomicsHistone H3K36 trimethylation is essential for multiple silencing mechanisms in fission yeast.
In budding yeast, Set2 catalyzes di- and trimethylation of H3K36 (H3K36me2 and H3K36me3) via an interaction between its SRI domain and C-terminal repeats of RNA polymerase II (Pol2) phosphorylated at Ser2 and Ser5 (CTD-S2,5-P). H3K36me2 recruits the Rpd3S histone deacetylase complex to repress crypt...
ORGANISM(S): Schizosaccharomyces pombe 
2016-02-04 | E-GEOD-66821 | biostudies-arrayexpress
UnknownRNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease
Not available
EMPIAR-11824 | biostudies-other
TranscriptomicsmiR-140 deficiency effect on the chondrocytes
Analysis of mouse chondrocytes lacking the microRNA-140. MicroRNAs are genomically encoded small RNAs to regulate the gene expression. miR-140 shows high expression in cartilage. Results provide insight into the molecular mechanisms underlying miR-140 function in chondrocytes. Keywords: Expression ...
ORGANISM(S): Mus musculus 
2010-01-01 | E-GEOD-16007 | biostudies-arrayexpress
TranscriptomicsExpression data from colon and livers of mice
Here we describe our unprecedented approach in proposing parsley (PAR) as a nutraceutical intervention in inflammatory bowel disease (IBD) using a mouse model of dextran sodium sulphate (DSS)-induced colitis, following a multi-integrated-omics analysis. PAR supplementation (n=7) significantly improv...
ORGANISM(S): Mus musculus 
2014-01-24 | E-GEOD-54349 | biostudies-arrayexpress
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