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TranscriptomicsListeria monocytogenes EGD and EGD-e
Transcriptional profile after growth in MM (minimal medium (Premaratne et al. 2001) supplemented with 50 mM Glucose. Note: strain "EGD" has not been deposited at ATCC/NCTC. It is a derivative of the original Murray strain (Murray et al. 1926), obtained from S.H.E. Kaufmann. Strain "E...
ORGANISM(S): Listeria monocytogenes 
2008-11-30 | E-GEOD-12146 | biostudies-arrayexpress
TranscriptomicsDNA methylation in postmortem brain samples from autism cases and controls
We used the Illumina 450KMethylation BeadChip to measure DNA methylation at 485,512 loci across the genome for 40 postmortem brain samples. The purpose of our study was to identify differentially methylated regions (DMRs) associated with autism. Samples included 16 temporal cortex brain tissue sampl...
ORGANISM(S): Homo sapiens 
2013-12-12 | E-GEOD-53162 | biostudies-arrayexpress
UnknownDietary pyridoxine controls efficacy of vitamin B6-auxotrophic tuberculosis vaccine bacillus Calmette-Guerin ΔureC::hly Δpdx1 in mice.
Not available
S-EPMC4049106 | biostudies-literature
MetabolomicsGut microbiome dysbiosis drives metabolic dysfunction in Familial dysautonomia
Familial dysautonomia (FD) is a rare genetic neurologic disorder caused by impaired neuronal development and progressive degeneration of both the peripheral and central nervous systems. FD is monogenic, with >99.4% of patients sharing an identical point mutation in the elongator acetyltransferase co...
2022-12-06 | MTBLS5138 | MetaboLights
ProteomicsCentral nervous system involvement of acute lymphoblastic leukemia depends on mRNA translation and complement component 3
Central nervous system (CNS) dissemination of B-precursor acute lymphoblastic leukemia (B-ALL) has a poor prognosis and remains a therapeutic challenge with few recent advances in therapy. Leptomeningeal disease is particularly common in the high risk subgroup of KMT2A-rearranged B-ALL (KMT2A-r B-AL...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD022411 | Pride
Lc-ms Leukemia Lfq 
GenomicsCharacterization of SOC1’s central role in flowering by the identification of its upstream and downstream regulators
The transition from vegetative to reproductive development is one of the most important phase changes in the plant life cycle. This step is controlled by various environmental signals that are integrated at the molecular level by so-called floral integrators. One such floral integrator in Arabidopsi...
ORGANISM(S): Arabidopsis thaliana 
2013-04-09 | E-GEOD-45846 | biostudies-arrayexpress
UnknownRelationship of Psychological Characteristics to Daily Life Ischemia: An Analysis From the National Heart, Lung, and Blood Institute Psychophysiological Investigations in Myocardial Ischemia.
Not available
S-EPMC8976783 | biostudies-literature
TranscriptomicsSubunit-specific vs. non-selective proteasome modulation in limiting inflammation in experimental colitis
Inflammatory bowel disease (IBD), comprising CrohnM-BM-4s disease and Ulcerative colitis, is characterized by chronic relapsing inflammation of the gut. It has been shown that increased proteasomal activity is associated with the expression of immunoproteasomes, which enhances NF-kB activation and t...
ORGANISM(S): Mus musculus 
2010-07-06 | E-GEOD-18163 | biostudies-arrayexpress
TranscriptomicsMicroRNA miR-223 constrains lethal inflammation during Mycobacterium tuberculosis infection
The molecular mechanisms that control innate cell recruitment during chronic infection and inflammation, such as tuberculosis (TB), are incompletely understood. During TB, myeloid cells infiltrate the lung and sustain local inflammation. We identified microRNA (miR)-223 as one of the most abundant n...
ORGANISM(S): Homo sapiens 
2014-04-21 | E-GEOD-39163 | biostudies-arrayexpress
TranscriptomicsLung-resident myeloid-derived suppressor cells display dual functionality in experimental tuberculosis
Using cell-based approaches and experimental mouse models for pulmonary TB we unveiled MDSCs as new myeloid populations directly interacting with Mycobacterium tuberculosis (Mtb). MDSCs readily phagocytosed Mtb, released proinflammatory (IL-6, IL-1M-NM-1) and immunomodulatory (IL-10) cytokines while...
ORGANISM(S): Mus musculus 
2014-12-21 | E-GEOD-57124 | biostudies-arrayexpress
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