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TranscriptomicsHalobacterium NRC-1, EMS Stress Response
100mM EMS was added to mid-log phase Halobacterium NRC-1 cultures. After constant stress of EMS for 30 minutes, cultures were spun down and pellets were re-suspended in same volume of GN101 media. Cultures were then harvested by centrifugation and pellets were snap frozen on a dry-ice ethanol bath. ...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-27 | E-GEOD-7609 | biostudies-arrayexpress
TranscriptomicsHalobacterium NRC-1, NiSO4 Stress Response series 2
Given that transition metals are essential cofactors in central biological processes, misallocation of the wrong metal ion to a metalloprotein can have resounding and often detrimental effects on diverse aspects of cellular physiology. Therefore, in an attempt to characterize unique and shared respo...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-06-11 | E-GEOD-7613 | biostudies-arrayexpress
TranscriptomicsHalobacterium NRC-1, CoSO4 Stress Response series 2
Given that transition metals are essential cofactors in central biological processes, misallocation of the wrong metal ion to a metalloprotein can have resounding and often detrimental effects on diverse aspects of cellular physiology. Therefore, in an attempt to characterize unique and shared respo...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-06-11 | E-GEOD-7612 | biostudies-arrayexpress
TranscriptomicsCoordination of frontline defense mechanisms under severe oxidative stress.
Oxidative stress (OS) results from genetic defects or stressful environmental challenges that cause unchecked production of reactive oxygen species (ROS). OS has been implicated in many diseases due to its wide ranging damage to nucleic acids, proteins and lipids. Using Halobacterium salinarum NRC...
ORGANISM(S): Halobacterium salinarum 
2010-05-26 | E-GEOD-17515 | biostudies-arrayexpress
Proteomics,MultiomicsHalo_itraq12
Proteins harvested from cultures recovering from 0Gy (control) or 2500Gy (experimental) of gamma irradiation stress and labeled with iTRAQ, multiplex sample #12 with three time points 30, 40, 60 min during recovery compared against common reference; Whitehead et al., 2006 Mol Syst Biol. 2(47). Repli...
ORGANISM(S): Halobacterium Nrc-1 (halobacterium) 
2006-12-31 | PAe000259 | PeptideAtlas
Proteomics,MultiomicsHalo_itraq11
Proteins harvested from cultures recovering from gamma irradiation stress and labeled with iTRAQ, multiplex sample #11 with three time points 30, 40, and 60 min during recovery compared against common reference; Whitehead et al., 2006 Mol Syst Biol. 2(47).
ORGANISM(S): Halobacterium Nrc-1 (halobacterium) 
2006-12-31 | PAe000245 | PeptideAtlas
TranscriptomicsH. salinarum transcriptome dynamics in response to 0.85mM extracellular copper
Halobacterium salinarum is a halophillic archea that is capable of sustaining growth despite dramatic changes to the concentration of ions in its extracellular environment. Here we studied H. salinarum's specific adaptation response to the transition metal copper. Analysis utilized pre-treatment (t...
ORGANISM(S): Halobacterium sp. NRC-1 
2012-06-29 | E-GEOD-39028 | biostudies-arrayexpress
TranscriptomicsHalobacterium growth in standard growth media: time course
We report detailed characterization of physiological changes encoded by 63% of all genes within the archaeon Halobacterium salinarum subsp. NRC-1 during routine laboratory growth. While the majority of these changes occur during the transition from rapid exponential growth to the stationary phase, ...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-14 | E-GEOD-14832 | biostudies-arrayexpress
TranscriptomicsHalobacterium growth with added uracil: time course
We report detailed characterization of physiological changes encoded by 63% of all genes within the archaeon Halobacterium salinarum subsp. NRC-1 during routine laboratory growth. While the majority of these changes occur during the transition from rapid exponential growth to the stationary phase, ...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-14 | E-GEOD-14835 | biostudies-arrayexpress
TranscriptomicsHalobacterium delta-ura3 growth with added uracil: time course
We report detailed characterization of physiological changes encoded by 63% of all genes within the archaeon Halobacterium salinarum subsp. NRC-1 during routine laboratory growth. While the majority of these changes occur during the transition from rapid exponential growth to the stationary phase, ...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-14 | E-GEOD-14836 | biostudies-arrayexpress
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