Sort   by:  
 Page size 
TranscriptomicsSlicing-Independent RISC Activation Requires the Argonaute PAZ Domain
Small RNAs regulate the genetic networks through a ribonucleoprotein complex called the RNA induced silencing complexes (RISC), which in mammals contains at its center one of four Argonaute proteins (Ago1-4). A key regulatory event in the RNAi and miRNA pathways is Ago loading, where double stranded...
ORGANISM(S): Homo sapiens 
2012-07-12 | E-GEOD-39146 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression profiling of mouse liver tissue samples after treated with various anti-HCV shRNAs
RNA interference (RNAi) is becoming routine in scientific discovery and treating human disease. However, its applications are hampered by unwanted effects. The RNA-Seq analyses from mouse liver samples expressing various anti-HCV shRNAs show that weak base-pairing in both seed and 3’ regions is requ...
ORGANISM(S): Mus musculus 
2014-10-03 | E-GEOD-55131 | biostudies-arrayexpress
UnknownPersistent interferon signaling and clonal expansion mark early events in DNA methylation damage-induced liver cancer.
Not available
S-EPMC12621704 | biostudies-literature
TranscriptomicsEccentric exercise activates novel transcriptional regulation of hypertrophic signaling pathways
Full title: Eccentric exercise activates novel transcriptional regulation of hypertrophic signaling pathways not affected by hormone changes. Unaccustomed eccentric exercise damages muscle tissue stimulating mechanisms of recovery and remodeling that may be affected by cellular protection by the sex...
ORGANISM(S): Homo sapiens 
2009-12-16 | E-GEOD-19062 | biostudies-arrayexpress
TranscriptomicsLinkage of genomic biomarkers to whole organism endpoints in a Toxicity Identification Evaluation (TIE)
Aquatic organisms are exposed to many toxic chemicals and interpreting the cause and effect relationships between occurrence and impairment is difficult. Toxicity Identification Evaluation (TIE) provides a systematic approach for identifying responsible toxicants. TIE relies on relatively uninforma...
ORGANISM(S): Ampelisca abdita 
2012-12-21 | E-GEOD-41463 | biostudies-arrayexpress
UnknownA megastudy of text-based nudges encouraging patients to get vaccinated at an upcoming doctor's appointment.
Not available
S-EPMC8157982 | biostudies-literature
UnknownA Randomized Trial of Behavioral Nudges Delivered Through Text Messages to Increase Influenza Vaccination Among Patients With an Upcoming Primary Care Visit.
Not available
S-EPMC10798571 | biostudies-literature
UnknownGENCODE: massively expanding the lncRNA catalog through capture long-read RNA sequencing.
Not available
S-EPMC11565817 | biostudies-literature
UnknownMeta-analysis of Parkinson's disease: identification of a novel locus, RIT2.
Not available
S-EPMC3354734 | biostudies-literature
UnknownExpanded encyclopaedias of DNA elements in the human and mouse genomes.
Not available
S-EPMC7410828 | biostudies-literature
Sort   by:  
 Page size