Sort   by:  
 Page size 
ProteomicsPlant homeodomain targeting cyclic peptides allosterically modulate KDM7 histone demethylase activity
Here we report the discovery of a set of potent de-novo cyclic peptides (CPs) targeting different binding sites on KDM7B. One CP (OC9) bound directly to the KDM7 PHD-finger, as supported by bio-layer interferometry (BLI), isothermal calorimetry (ITC), hydrogen-deuterium exchange mass spectrometry (H...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD027151 | Pride
Kdm7 Proteomics Cyclic peptide Ptm 
TranscriptomicsKDM7 is a dual demethylase for histone H3 lysines 9 and 27 and functions in brain development
The roles of histone demethylase KDM7 in gene expression were analyzed by gene expression profiling experiments with mouse neuroblastoma cell line Neuro2A. Keywords: mouse neuroblastoma, Neuro2A, gene expression profiling, microarray, Affimetrix M430 2.0 chip In order to examine the effect of KDM7 i...
ORGANISM(S): Mus musculus 
2010-03-06 | E-GEOD-17494 | biostudies-arrayexpress
TranscriptomicsKDM7 is a dual demethylase for histone H3 lysines 9 and 27 and functions in brain development
The roles of histone demethylase KDM7 in gene expression were analyzed by gene expression profiling experiments with the mouse neuroblastoma cell line Neuro2A.
ORGANISM(S): Mus musculus 
2010-03-01 | GSE17494 | GEO
GenomicsMus musculus
KDM7 is a dual demethylase for histone H3 lysines 9 and 27 and functions in brain development
PRJNA118929 | ENA
UnknownCatalysis by KDM6 Histone Demethylases - A Synergy between the Non-Heme Iron(II) Center, Second Coordination Sphere, and Long-Range Interactions.
Not available
S-EPMC10526731 | biostudies-literature
UnknownInvestigations on small molecule inhibitors targeting the histone H3K4 tri-methyllysine binding PHD-finger of JmjC histone demethylases.
Not available
S-EPMC6380468 | biostudies-literature
UnknownJMJD-1.2 controls multiple histone post-translational modifications in germ cells and protects the genome from replication stress.
Not available
S-EPMC5830613 | biostudies-literature
UnknownCyclic peptides target the aromatic cage of a PHD-finger reader domain to modulate epigenetic protein function.
Not available
S-EPMC10321576 | biostudies-literature
TranscriptomicsIllumina Microarray of T47D cell with or without KDM7A-DT silencing under normal and oxidative stress conditions
KDM7A Divergent Transcript (KDM7A-DT) is a stress-induced lncRNAs. In our previous studies, KDM7A-DT showed the most robust cellular phenotype alteration and a significant TP53-dependency upon oxidative and oncogenic stress induction. Since about 50% of human breast cancers have mutant p53 and assoc...
ORGANISM(S): Homo sapiens 
2023-05-01 | E-MTAB-11818 | biostudies-arrayexpress
Sort   by:  
 Page size