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ProteomicsMouse brain LC-MS - KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a
To investigate the molecular mechanisms by which KIBRA regulates exosome secretion, we performed mass spectral (MS) analysis and an isobaric tag for relative and absolute quantitation (iTRAQ) assay to screen the differentially-expressed proteins in the brains of KIBRA-KO mice compared with their WT ...
ORGANISM(S): Mus musculus (Mouse) 
2019-04-02 | PXD012430 | Pride
Kibra Brain Lc-ms Mouse 
ProteomicsKIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss
The dynamic function of synapses is critical for encoding memories in the brain. Pathogenic tau obstructs glutamatergic synapse function by blocking long-term potentiation (LTP), representing a key mechanism underlying memory impairment in Alzheimer s disease (AD). Here we developed a strategy for K...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-10-11 | MSV000090510 | MassIVE
UnknownMECP2 impairs neuronal structure by regulating KIBRA.
Not available
S-EPMC5609186 | biostudies-literature
UnknownKIBRA modulates directional migration of podocytes.
Not available
S-EPMC2551571 | biostudies-literature
UnknownKIBRA regulates amyloid β metabolism by controlling extracellular vesicles secretion.
Not available
S-EPMC8983338 | biostudies-literature
UnknownLoss of KIBRA function activates EGFR signaling by inducing AREG.
Not available
S-EPMC6057453 | biostudies-literature
UnknownCortical tension promotes Kibra degradation via Par-1.
Not available
S-EPMC10881160 | biostudies-literature
UnknownKIBRA regulates Hippo signaling activity via interactions with large tumor suppressor kinases.
Not available
S-EPMC3048666 | biostudies-literature
UnknownThe role of KIBRA in reconstructive episodic memory.
Not available
S-EPMC6016870 | biostudies-literature
UnknownRegulation of AMPA receptor function by the human memory-associated gene KIBRA.
Not available
S-EPMC3200575 | biostudies-literature
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