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ProteomicsKIF1A, TANC2, liprin-a2 interactomes identified by AP-MS.
The mechanisms by which motor proteins are loaded on vesicles and how cargos are captured at appropriate sites remain unclear. To better understand how KIF1A-based transport is regulated, we identified the KIF1A interactome and focused on three binding partners, the calcium binding protein Calmoduli...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-07-12 | PXD010080 | Pride
Ap-ms Tanc2 Liprin-a Lc-msms. Kif1a 
TranscriptomicsKIF1A promotes neuroendocrine differentiation in prostate cancer by regulating the OGT-mediated O-GlcNAcylation
Background: Treatment-related neuroendocrine prostate cancer (t-NEPC) is a highly aggressive form of prostate cancer (PCa). Understanding the molecular mechanisms driving t-NEPC may provide valuable therapeutic strategies. Methods: we performed a pan-cancer differential mRNA abundance analysis of ne...
ORGANISM(S): Homo sapiens 
2024-10-23 | GSE266283 | GEO
GenomicsKIF1A promotes neuroendocrine differentiation in prostate cancer by regulating the OGT-mediated O-GlcNAcylation
KIF1A promotes neuroendocrine differentiation in prostate cancer by regulating the OGT-mediated O-GlcNAcylation
PRJNA1106499 | ENA
ProteomicsNovel Kinesin Family 1A Variants Linked to Atypical Parkinsonism Elicit Altered Neuronal TDP-43 Interactions and Dendritic Atrophy
We used patient induced pluripotent stem cells (IPSC) derived neurons from a patient with two mutations in KIF1A to evaluate the quantitative changes to KIF1A protein interaction, relative to wild-type control IPSC-motor neurons, using an anti-KIF1A antibody during immunoprecipitation. Given the rel...
ORGANISM(S): Homo sapiens (Human) 
2025-08-26 | PXD067234 | Pride
Kif1a Ipsc motor neurons Tdp-43 
Genomics
KIF1A Long read sequence
PRJNA1244412 | ENA
Genomics
KIF1A long read phasing
PRJNA1244324 | ENA
UnknownModeling the motion of disease-associated KIF1A heterodimers.
Not available
S-EPMC10698283 | biostudies-literature
UnknownDistinct Clinical Phenotypes in KIF1A-Associated Neurological Disorders Result from Different Amino Acid Substitutions at the Same Residue in KIF1A.
Not available
S-EPMC12109325 | biostudies-literature
UnknownSpecific KIF1A-adaptor interactions control selective cargo recognition.
Not available
S-EPMC8298099 | biostudies-literature
UnknownAssociation of variants in the KIF1A gene with amyotrophic lateral sclerosis.
Not available
S-EPMC9597953 | biostudies-literature
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