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TranscriptomicsGene expression changes associated with the anti-angiogenic effect of KLK3 (PSA) on HUVECs
Kallikrein-related peptidase 3 (KLK3, also known as prostate-specific antigen, PSA) is a chymotrypsin-like kallikrein that has been shown to have anti-angiogenic properties. KLK3 expression in prostate cancer is associated with low microvessel density. We have previously shown in a human umbilical v...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-9869 | biostudies-arrayexpress
TranscriptomicsaCGH of neuroblastic tumors
Title: Array-based gene expression, CGH and tissue data define a 12q24 gain in neuroblastic tumors with prognostic implication. Background: Neuroblastoma has successfully served as a model system for the identification of neuroectoderm-derived oncogenes. However, in spite of various efforts, only a ...
ORGANISM(S): Homo sapiens 
2010-05-05 | E-GEOD-18143 | biostudies-arrayexpress
TranscriptomicsArray-based gene expression in neuroblastic tumors
Title: Array-based gene expression, CGH and tissue data define a 12q24 gain in neuroblastic tumors with prognostic implication. Background: Neuroblastoma has successfully served as a model system for the identification of neuroectoderm-derived oncogenes. However, in spite of various efforts, only a ...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-18139 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Dm-aKG treated intestinal stem cells (ISCs) and controls
The object of this study was to investigate how aKG impacts mouse intestinal stem cell (ISCs) function and fate decisions in vivo. Mice were treated for 7 days with twice daily aKG IP injections after which ISCs were FACS sorted and transcriptomically anayzled. This revealed a striking set of secret...
ORGANISM(S): Mus musculus 
2025-05-02 | E-MTAB-15105 | biostudies-arrayexpress
GenomicsFacilitates chromatin transcription complex is a marker and target of aggressive cancers with lower survival rates
The Facilitates Chromatin Transcription (FACT) is involved in chromatin remodeling during transcription, replication and DNA repair and is considered to be an ubiquitously expressed complex that has no known associations with any disease. However, we discovered that FACT is expressed in very limited...
ORGANISM(S): Homo sapiens 
2013-03-22 | E-GEOD-45393 | biostudies-arrayexpress
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